Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Social Media Addiction, Perceived Stress, Emotional Intelligence, and Cyberbullying Among Thai Adolescents During the Transition from the COVID-19 Pandemic to the Endemic Phase. [PDF]
Rodpet S, Thaweekoon T, Napa W.
europepmc +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Individual, community, and societal drivers of adolescent peer violence in Asella, Ethiopia: A school-based cross-sectional study utilizing the socio-ecological model. [PDF]
Demissie A +7 more
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Experiences of violence among people with severe mental illness: social, biographical and institutional factors (EVIO). A study protocol for a mixed-methods study. [PDF]
Krumm S +7 more
europepmc +1 more source
Personality and mental health as mediators linking childhood maltreatment to intimate partner violence victimization: a Mendelian randomization-direction of causation twin study. [PDF]
Pezzoli P +5 more
europepmc +1 more source
Perceived Paternal Acceptance-Rejection, Self-Perception, and Peer Victimization in Preadolescents with and Without Special Educational Needs. [PDF]
Christou AI +3 more
europepmc +1 more source
Adult Men's Sexual Assault Victimization and Condom Use Resistance: A Preliminary Investigation. [PDF]
Kirwan M +3 more
europepmc +1 more source

