Results 41 to 50 of about 2,112,898 (232)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

H.266/VVC fast intra prediction using Sobel edge features

Electronics Letters, 2021
Versatile video coding is the next‐generation video coding standard. Compared with the previous high efficiency video coding standard, versatile video coding reduces 30% or more bitrate but requires significantly higher encoding complexity.
Shih‐Hsuan Yang, Sheng‐Jung Hsiao
doaj   +1 more source

Edge Computing-Based SAT-Video Coding for Remote Sensing

IEEE Access, 2022
This paper proposes an edge computing-based video coding implementation on an Earth observation satellite (SAT-video coding), which can encode video using limited resources and the power of mini/microsatellites.
Trong-An Bui, Pei-Jun Lee, Kuan-Yu Chen, Chia-Ray Chen, Cynthia S. J. Liu, Hsin-Chia Lin   +5 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Deep Learning‑Driven Video Coding: Methods, Progress, and Perspectives

Shuju Caiji Yu Chuli
With the explosive growth of video data， limited network bandwidth and high computational demands pose significant challenges for video transmission and storage. In this context， the continuous development of efficient video coding methods is of critical
HE Xiaohai, LI Xinlei, WEI Haitao, BI Xiaodong, NIE Yaojia, XIONG Zhina, ZHANG Haoyan, XIONG Shuhua   +7 more
doaj   +1 more source

Multiple description video coding based on zero padding [PDF]

, 2004
This paper proposes a simple multiple description video coding approach based on zero padding theory. It is completely based on pre- and post-processing, which require no modifications to the source codec.
Redmill, DW, Canagarajah, CN, Wang, D, Bull, DR   +3 more
core   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

A Semantic Communication and VVC Based Hybrid Video Coding System

IEEE Access
Requirements of next-generation video applications are becoming a challenge for conventional video coding systems, although they have evolved over decades to accommodate the most demanding of current video applications.
Prabhath Samarathunga, Yasith Ganearachchi, Thanuj Fernando, Adhuran Jayasingam, Indika Alahapperuma, Anil Fernando   +5 more
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source