Results 41 to 50 of about 41,400 (259)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Curvelet transform based feature extraction and selection for multimedia event classification

Journal of King Saud University: Computer and Information Sciences, 2022
Multimedia event classification has been one of the major endeavors in video event analysis. For event identification, feature extraction plays a critical role, merely distinguishing the right features becomes a challenging job.
Kaavya Kanagaraj, G.G. Lakshmi Priya
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A Novel Technique to Detect and Track Multiple Objects in Dynamic Video Surveillance Systems.

International Journal of Interactive Multimedia and Artificial Intelligence, 2022
Video surveillance is one of the important state of the art systems to be utilized in order to monitor different areas of modern society surveillance like the general public surveillance system, city traffic monitoring system, and forest monitoring ...
M. Adimoolam, Senthilkumar Mohan, John A., Gautam Srivastava   +3 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

ODC-net: Scalable and efficient object detection and classification in multi-object CCTV environments using deep transformer YOLO

Franklin Open
The increasing demand for real-time, accurate, and scalable surveillance systems is driven by the rapid rise in urban Closed-Circuit Television (CCTV) deployments, with global video surveillance expected to generate over 3 billion video hours daily ...
Sridhara Murthy B, Gandla Madhu, Varaganti Manisha, Muttukuri Madhu Krishna, Padmam Divyavalli, Reteneni Naveen   +5 more
doaj   +1 more source

Efficient Video Object Detection Based on Partitioning [PDF]

Jisuanji gongcheng
To address the challenge of balancing accuracy requirements and computational costs of object detection using deep neural networks for video analysis tasks, existing methods predominantly use entire video frames as units for computational resource ...
HUANG Shuyi, TAN Guang
doaj   +1 more source

UnCanny: Exploiting Reversed Edge Detection as a Basis for Object Tracking in Video

Journal of Imaging, 2021
Few object detection methods exist which can resolve small objects (
Wesley T. Honeycutt, Eli S. Bridge
doaj   +1 more source