Results 151 to 160 of about 1,598,295 (269)

“Two‐For‐One”: 4D Cardiac and Pulmonary MR Imaging From a Single Acquisition Using bSTAR

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 5, Page 2213-2227, November 2026.
ABSTRACT Purpose To generate 4D (3D+time) images of both the heart and lungs using a single volumetric radial free‐breathing bSSFP dual echo acquisition (bSTAR) with two image reconstructions within a single pipeline deployed inline at 0.55 and 1.5 T.
Pierre Daudé   +9 more
wiley   +1 more source

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran   +2 more
wiley   +1 more source

Maternal and Postnatal Effects of Poly I:C‐Induced Intrauterine Inflammation and Rytvela, a Non‐Competitive IL‐1R Antagonist, in the Pregnant Spiny Mouse

open access: yesDevelopmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Maternal infection‐induced inflammation during pregnancy is associated with adverse neurodevelopment. Rytvela, an allosteric IL‐1 receptor antagonist, reduces IL‐1β‐mediated pathology in fetal rodents and sheep. However, its effects on TLR3‐mediated inflammation and subsequent offspring growth and behavior remain unclear. Using precocial spiny
Nhi T. Tran   +7 more
wiley   +1 more source

Simultaneous T2, T2*, and R2′ Mapping for Multiple Sclerosis Using Nonlinear Model‐Based Reconstruction of Undersampled Radial RARE‐EPI MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1872-1892, October 2026.
ABSTRACT Purpose To demonstrate the synergy of undersampled radial 2in1‐RARE‐EPI acquisition and nonlinear model‐based reconstruction for accelerated and simultaneous T2, T2*, and R2′ mapping in brains of patients with multiple sclerosis (MS). Methods 2in1‐RARE‐EPI combines a RARE module with an EPI module to capture T2 and T2* information.
Jose Raul Velasquez Vides   +16 more
wiley   +1 more source

Implementation of the In Vitro Seizure Liability Assay (iLAseizure) in Drug Discovery and Development: Mechanism of Action Case Studies

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Central nervous system (CNS) liabilities remain a significant cause of attrition during small molecule drug development. We previously developed the in vitro seizure liability assay (iLAseizure), a new approach methodology (NAM) comprising a human induced pluripotent stem cell neuron microelectrode array (MEA) assay coupled with a panel of ...
Kimberly Rockley   +5 more
wiley   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6179-6198, October 2026.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville   +6 more
wiley   +1 more source

Year-round movement of emperor penguin colonies observed from space. [PDF]

open access: yesCommun Earth Environ
Macdonald GJ   +6 more
europepmc   +1 more source

Effects of High‐Fidelity Simulation Training on Learning Outcomes and Satisfaction for Practising Registered Nurses: A Systematic Review and Meta‐Analysis

open access: yesJournal of Clinical Nursing, Volume 35, Issue 10, Page 4174-4183, October 2026.
ABSTRACT Background Ample evidence has shown the benefit of high‐fidelity simulation (HFS) in promoting learning in pre‐licensure nursing students, but the evidence for practising registered nurses has not been synthesised. Objective To evaluate the effects of HFS training on learning outcomes and satisfaction in practising registered nurses.
Jie Zhou   +4 more
wiley   +1 more source

Lonicera japonica‐Derived Nanovesicles Ameliorate Acute Lung Injury by Suppressing Neutrophil Extracellular Traps Formation in Mice

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 33, 4 September 2026.
(A) Isolation and purification of LDNVs. (B) Establishment of the ALI model and LDNVs delivery. (C) Therapeutic mechanisms of LDNVs in treating ALI. This scheme figure was drawn by Figdraw, ID: IUIIO21222. ABSTRACT Acute lung injury (ALI) is a lethal respiratory disease.
Xi Lin   +10 more
wiley   +1 more source

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