A Versatile Processing Workflow to Enable Pathogen Detection in Clinical Samples from Organs Using VIDISCA [PDF]
In recent years, refined molecular methods coupled with powerful high throughput sequencing technologies have increased the potential of virus discovery in clinical samples.
Ad de Groof +2 more
exaly +4 more sources
A Novel Simian Adenovirus Associating with Human Adenovirus Species G Isolated from Long-Tailed Macaque Feces [PDF]
Metagenomics has demonstrated its capability in outbreak investigations and pathogen surveillance and discovery. With high-throughput and effective bioinformatics, many disease-causing agents, as well as novel viruses of humans and animals, have been ...
Juthamas Phadungsombat +2 more
exaly +4 more sources
Performance of VIDISCA-454 in Feces-Suspensions and Serum [PDF]
Virus discovery combining sequence unbiased amplification with next generation sequencing is now state-of-the-art. We have previously determined that the performance of the unbiased amplification technique which is operational at our institute, VIDISCA ...
Barbera D.C. van Schaik +2 more
exaly +4 more sources
Identification of a Novel Human Rhinovirus C Type by Antibody Capture VIDISCA-454 [PDF]
Causative agents for more than 30 percent of respiratory infections remain unidentified, suggesting that unknown respiratory pathogens might be involved.
Bas B Oude Munnink +2 more
exaly +4 more sources
A Sensitive Assay for Virus Discovery in Respiratory Clinical Samples [PDF]
In 5-40% of respiratory infections in children, the diagnostics remain negative, suggesting that the patients might be infected with a yet unknown pathogen.
Wandry Rodrigues Faria +2 more
exaly +3 more sources
Divergent Rhabdovirus Discovered in a Patient with New-Onset Nodding Syndrome [PDF]
A divergent rhabdovirus was discovered in the bloodstream of a 15-year-old girl with Nodding syndrome from Mundri West County in South Sudan. Nodding syndrome is a progressive degenerative neuropathy of unknown cause affecting thousands of individuals in
Arthur W. D. Edridge +5 more
doaj +2 more sources
Influenza and other respiratory viruses involved in severe acute respiratory disease in northern Italy during the pandemic and postpandemic period (2009-2011). [PDF]
Since 2009 pandemic, international health authorities recommended monitoring severe and complicated cases of respiratory disease, that is, severe acute respiratory infection (SARI) and acute respiratory distress syndrome (ARDS). We evaluated the proportion of SARI/ARDS cases and deaths due to influenza A(H1N1)pdm09 infection and the impact of other ...
Pariani E +9 more
europepmc +2 more sources
Metagenomic analysis of a sample from a patient with respiratory tract infection reveals the presence of a γ-papillomavirus [PDF]
Previously unknown or unexpected pathogens may be responsible for that proportion of respiratory diseases in which a causative agent cannot be identified. The application of broad-spectrum, sequence independent virus discovery techniques may be useful to
Marta eCanuti +13 more
doaj +2 more sources
A Novel Virus Causes Scale Drop Disease in Lates calcarifer. [PDF]
From 1992 onwards, outbreaks of a previously unknown illness have been reported in Asian seabass (Lates calcarifer) kept in maricultures in Southeast Asia. The most striking symptom of this emerging disease is the loss of scales.
Ad de Groof +14 more
doaj +2 more sources
Persistent viremia by a novel parvovirus in a slow loris (Nycticebus coucang) with diffuse histiocytic sarcoma [PDF]
Cancer is one of the leading health concerns for human and animal health. Since the tumorigenesis process is not completely understood and it is known that some viruses can induce carcinogenesis, it is highly important to identify novel oncoviruses and ...
Marta eCanuti +8 more
doaj +2 more sources

