Results 201 to 210 of about 7,017,367 (314)

High School Students' Views of Science in a University Science Internship with Cogenerative Dialogues

, 2017
Gabriel Micah Hayes
openalex   +1 more source

Broadened View [PDF]

Deutsches Ärzteblatt international, 2016
openaire   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

High-throughput multi-camera array microscope platform for automated 3D behavioral analysis of swimming zebrafish larvae. [PDF]

Commun Biol
Chen H, Li K, Kreiss L, Reamey P, Pierce LX, Zhang R, Da Luz R, Chaware A, Kim K, Cook CB, Yang X, Lerner JF, Doman J, Bègue A, Efromson J, Harfouche M, Horstmeyer G, McCarroll MN, Horstmeyer R.   +18 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Abundance in secret: a review of the genus <i>Leptobrachium</i> (Anura, Megophryidae) in India, with descriptions of two new species. [PDF]

PeerJ
Sarmah ANDA, Garg S, Tajo T, Upadhyaya K R, Hanken J, Biju SD.   +5 more
europepmc   +1 more source

Analysis of Views from Lake-side and Mountain-side Streets at 12 Stations around Lake Biwa Rim

Minori Hayashi, Shinichi Todoroki
openalex   +2 more sources

https://www.altex.org/index.php/altex/article/view/1339

, 2019
A. T. Krebs, Tanja Waldmann, Martin F. Wilks, Barbara M. A. van Vugt‐Lussenburg, Bart van der Burg, Andrea Terron, Thomas Steger‐Hartmann, Joëlle Rüegg, Costanza Rovida, Emma Pedersen, Giorgia Pallocca, Mirjam Luijten, Sofia Batista Leite, Stefan Kustermann, Hennicke Kamp, Julia Hoeng, Philip Hewitt, Matthias Herzler, Jan G. Hengstler, Tuula Heinonen, Thomas Härtung, Barry Hardy, Florian Gantner, Ellen Fritsche, Kristina Fant, Janine Ezendam, Thomas E. Exner, Torsten Dunkern, Daniel R. Dietrich, Sandra Coecke, François Busquet, Albert Braeuning, Olesja Bondarenko, Susanne Hougaard Bennekou, Mario Beilmann, Marcel Leist   +35 more
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Personal View [PDF]

BMJ, 1968
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Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source