Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis [PDF]
Synaptic transmission between midbrain dopamine neurons and target neurons in the striatum is essential for the selection and reinforcement of movements. Recent evidence indicates that nigrostriatal dopamine neurons inhibit striatal projection neurons by
Gu, Chenghua +3 more
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Vigabatrin — new data on indications and safety in paediatric epilepsy
Weronika Golec +4 more
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Musicogenic Epilepsy in An Infant
A 6-month-old infant with seizures triggered by loud music, especially specific songs of the Beatles, is reported from Chang Gung Children’s Hospital at Linkou, Taoyuan, Taiwan.
J Gordon Millichap
doaj +1 more source
A 47-Year Old Female with Muscular Rigidity, New-Onset Diabetes and Hypothyroidism [PDF]
Background This case highlights a rare but devastating neurologic condition, Stiff Person Syndrome (SPS). While symptoms of muscular rigidity andspasms areassocia ted with numerous neuromuscular conditions, the association between SPS, autoimmune ...
Valentino, MD, PhD, Michael A.
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Downbeat nystagmus: aetiology and comorbidity in 117 patients [PDF]
Objectives: Downbeat nystagmus (DBN) is the most common form of acquired involuntary ocular oscillation overriding fixation. According to previous studies, the cause of DBN is unsolved in up to 44% of cases.
Brandt, Thomas +3 more
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Comparison of the Hepatotoxicity of Carbamazepine, Sodium Valproate, Phenytoin, Lamotrigine, and Vigabatrin in a Rat Model [PDF]
Vahid Ramezani +3 more
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The subthalamic nucleus (STN) plays a crucial role as a regulator of basal ganglia outflow but also influences the activity of cortical and limbic structures, so that it is widely used as a therapeutic target in different brain diseases, including ...
Laura Gey +2 more
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Efficacy and safety of vigabatrin in the long‐term treatment of refractory epilepsy. [PDF]
C Rémy, D Beaumont
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Avaliamos a eficácia da vigabatrina (VGB) como monoterapia inicial para síndrome de West (SW), os seus efeitos colaterais e a evolução a curto prazo do eletrencefalograma (EEG), num estudo prospectivo, aberto e não controlado.
Adélia Maria de Miranda Henriques-Souza +2 more
doaj +1 more source
Utility of the Lethargic (lh/lh) Mouse Model of Absence Seizures in Predicting the Effects of Lamotrigine, Vigabatrin, Tiagabine, Gabapentin, and Topiramate Against Human Absence Seizures [PDF]
David A. Hosford, Ying Wang
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