Results 91 to 100 of about 141,825 (272)

Regional Standardization of CLL Management: Results of a Delphi Consensus Process

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino   +22 more
wiley   +1 more source

On efficiency of mean-variance based portfolio selection in DC pension schemes [PDF]

open access: yes
We consider the portfolio selection problem in the accumulation phase of a defined contribution (DC) pension scheme. We solve the mean-variance portfolio selection problem using the embedding technique pioneered by Zhou and Li (2000) and show that it is ...
Elena Vigna
core  

Induced high yielding amphiploid of Vigna radiata*Vigna mungo.

open access: yesCYTOLOGIA, 1990
Interspecific F1 hybrid (2x) between V. radiata var. T44 and V. mungo var. T9 showed intermediate morphological characters of both the parents and low pollen fertility (4.4%). Inspite of profused flowering there was no pod formation. However, on the contrary, the amphiploid (4x) obtained with the colchicine treatment of the F1 hybrid seedling exhibited
Kalpana Pande   +2 more
openaire   +2 more sources

Minimal Residual Disease as a Biological Trait: Rethinking Disease Persistence in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Minimal residual disease (MRD) has emerged as a central biomarker in hematologic malignancies, enabling highly sensitive detection of tumor persistence beyond conventional morphologic assessment and serving as an increasingly important surrogate endpoint in clinical trials.
Santino Caserta   +14 more
wiley   +1 more source

To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino   +16 more
wiley   +1 more source

Drivers of strigolactone diversity: P450s in strigolactone biosynthesis

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review summarizes the discovery and functional identification of cytochrome P450 in strigolactone biosynthesis, classifies and summarizes the members discovered so far, clarifies their biological significance, discusses the technology of strigolactone synthesis research, and finally describes some problems in strigolactone research and potential ...
Changbin Niu   +2 more
wiley   +1 more source

L’utilizzo di strumenti GIS per la ricerca geofisica e per la sorveglianza sismica

open access: yesGEOmedia, 2007
L’INGV costruisce e gestisce numerose reti di monitoraggio a livello nazionale e regionale per lo studio dei fenomeni geofisici, geologici e geochimici. Componente del servizio nazionale di protezione civile, gestisce i servizi di sorveglianza sismica e ...
Fawzi Doumaz   +3 more
doaj   +2 more sources

Investigating Equatorial Plasma Depletions through CSES-01 Satellite Data

open access: yesAtmosphere
Ionospheric plasma density irregularities, which are one of the primary sources of disturbance for the Global Navigation Satellite System, significantly impact the propagation of electromagnetic signals, leading to signal degradation and potential ...
Paola De Michelis   +7 more
doaj   +1 more source

The management of de-cumulation risks in a defined contribution environment [PDF]

open access: yes, 2005
The aim of the paper is to lay the theoretical foundations for the construction of a flexible tool that can be used by pensioners to find optimal investment and consumption choices in the distribution phase of a defined contribution pension scheme.
Gerrard, R. J. G.   +2 more
core  

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