Results 81 to 90 of about 62,238 (246)

First‐Line Treatment of IGHV‐Unmutated Chronic Lymphocytic Leukemia: A Network Meta‐Analysis of Targeted and Chemoimmunotherapy Regimens

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 375-383, August 2026.
ABSTRACT Immunoglobulin heavy chain variable region‐unmutated (IGHV‐U) chronic lymphocytic leukemia (CLL) represents a biologically aggressive subgroup with limited responsiveness to chemoimmunotherapy (CIT). To clarify the comparative effectiveness of available frontline options, we conducted a comprehensive Bayesian network meta‐analysis of ...
Santino Caserta   +13 more
wiley   +1 more source

From Time‐Limited Therapy to Treatment‐Free Observation: The Evolving Role of MRD in CLL Management

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 305-319, August 2026.
ABSTRACT The integration of measurable residual disease (MRD) into the management of chronic lymphocytic leukemia (CLL) has emerged as a major advance in risk stratification and trial design, particularly in the context of time‐limited, targeted regimens.
Enrica Antonia Martino   +13 more
wiley   +1 more source

L’utilizzo di strumenti GIS per la ricerca geofisica e per la sorveglianza sismica

open access: yesGEOmedia, 2007
L’INGV costruisce e gestisce numerose reti di monitoraggio a livello nazionale e regionale per lo studio dei fenomeni geofisici, geologici e geochimici. Componente del servizio nazionale di protezione civile, gestisce i servizi di sorveglianza sismica e ...
Fawzi Doumaz   +3 more
doaj   +2 more sources

Characteristics of the strong ground motion from the 24th August 2016 Amatrice earthquake

open access: yesAnnals of Geophysics, 2016
The 2016 August 24 Amatrice earthquake occurred at 03:36 local time in central Apennines Italy with an epicentre at 43.36°E, 38.76°N, Istituto Nazionale di Geofisica e Vulcanologia (INGV), few kilometers north of the city of Amatrice.
Marta Pischiutta   +3 more
doaj   +1 more source

Regional Standardization of CLL Management: Results of a Delphi Consensus Process

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 442-447, August 2026.
ABSTRACT The therapeutic landscape of chronic lymphocytic leukemia (CLL) has been profoundly transformed by the introduction of Bruton tyrosine kinase and BCL‐2 inhibitors. Despite improved survival outcomes, treatment selection remains complex, particularly in older patients with comorbidities, frailty, and increased infectious vulnerability.
Enrica Antonia Martino   +22 more
wiley   +1 more source

Non più e non ancora: un testo incompiuto di Maurice Merleau-Ponty, in Maurice Merleau-Ponty, La prosa del mondo, a cura di Pierre Dalla Vigna, pp. 7-16

open access: yes, 2019
Il testo incompiuto sulla filosofia del linguaggio di Merleau-Ponty, scritto negli anni cinquanta del Novecento e pubblicato postumo a cura di Claude Lefort nel 1964, viene interpretato come il punto di rottura rispetto all'interpretazione esistenziale ...
Pierre Dalla Vigna   +3 more
core   +1 more source

Minimal Residual Disease as a Biological Trait: Rethinking Disease Persistence in Hematologic Malignancies

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 320-337, August 2026.
ABSTRACT Minimal residual disease (MRD) has emerged as a central biomarker in hematologic malignancies, enabling highly sensitive detection of tumor persistence beyond conventional morphologic assessment and serving as an increasingly important surrogate endpoint in clinical trials.
Santino Caserta   +14 more
wiley   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

open access: yesAdvanced Science, Volume 13, Issue 38, 9 July 2026.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma   +11 more
wiley   +1 more source

Rumen methanogenic archaea and their correlation with enteric methane emission in ruminant animals: A systematic review and meta‐analysis

open access: yesJSFA reports, Volume 6, Issue 7, Page 265-279, July 2026.
Abstract Background Livestock, especially ruminants, are a major source of global methane emissions, primarily produced by methanogenic archaea during enteric fermentation. We performed a systematic review and meta‐analysis to account for factors that could influence the relationship between ruminal methanogenic populations and methane emissions, such ...
Arlan Araujo Rodrigues   +4 more
wiley   +1 more source

RNA interference in crop protection: opportunities and challenges during the transition to commercialization

open access: yesPest Management Science, Volume 82, Issue 7, Page 5971-5986, July 2026.
RNA interference (RNAi) technologies, host‐induced gene silencing (HIGS) and spray‐induced gene silencing (SIGS), potentially offer sustainable crop protection. However, efficacy, costs, regulatory clarity, and socio‐environmental impacts require further evaluation for broader use.
Elisabetta Sergi   +12 more
wiley   +1 more source

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