Results 61 to 70 of about 62,238 (246)

Bridging Randomized Trial Efficacy and Real‐World Effectiveness in Multiple Myeloma: Integrating Clinical Trials and Real‐World Evidence for Individualized Care

European Journal of Haematology, EarlyView.
ABSTRACT Multiple myeloma (MM) is predominantly a disease of older adults, yet the randomized clinical trials (RCTs) that define standards of care are conducted largely in younger, fitter, and less comorbid populations. This creates a systematic mismatch between the populations generating evidence and those receiving treatment in routine practice ...
Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Santino Caserta, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +13 more
wiley   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, EarlyView.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Introduzione. L’impossibilità di una Chiesa senza peccato

, 2019
La pedofilia, vero e proprio cancro che affligge la Chiesa, non è, a parere di Slavoj Žižek, un male che ha aggredito la struttura ecclesiastica dall'esterno, magari frutto delle perversioni della modernità, come riteneva Papa Benedetto XVI.
Pierre Dalla Vigna
core   +1 more source

Biased News Media and the Swing Voter's Decision in Repeated Games

The Manchester School, EarlyView.
ABSTRACT We consider a monopolistic, biased news media platform that attempts to influence the decision of swing voters with cheap talk when voting is costly and abstaining is an option. First, we demonstrate that, while no fully communicative equilibrium exists in a stage game, a partially truth‐revealing mixed‐strategy equilibrium exists.
Jooyong Jun, Jeong‐Yoo Kim
wiley   +1 more source

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

Plant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang, Anqin Gao, Tsz‐Yan Chan, Hafiz Mamoon Rehman, Sehar Nawaz, Sehrish Bashir, Noman Mahmood, Muhammad Wajid Ullah, Chunlin Long, Hon‐Ming Lam, Muhammad Arif   +10 more
wiley   +1 more source

Dallo spazio al territorio: Un sistema per l'Osservazione della Terra in tempo reale

GEOmedia, 2010
From space to land: a real time Earth Observation system from INGV Since many years INGV (Istituto Nazionale di Geofisica e Vulcanologia) in collaboration with several national and international research institutes, contributes to develop new spatial ...
Claudia Spinetti, Fawzi Doumaz, Fabrizia Buongiorno   +2 more
doaj   +2 more sources

Leaf Tissue‐Specific Phosphorus Allocation Is Linked to Leaf Lifespan in Chickpea Accessions

Plant, Cell &Environment, EarlyView.
ABSTRACT Plants strategically allocate phosphorus (P) among leaf tissues to support physiological functions. However, there is limited understanding of contrasting leaf cellular P‐allocation patterns and their physiological consequences. We quantified leaf P fractions, photosynthetic P‐use efficiency (PPUE), and P‐remobilisation efficiency (PRE) in ...
Xiaolong Feng, Peta L. Clode, Shuyan Li, Shu Tong Liu, Jiayin Pang, Gaétan Glauser, Kadambot H. M. Siddique, Hans Lambers   +7 more
wiley   +1 more source

Cuticular Waxes in Altered Environments and Their Role in Leaf Water Loss Dynamics

Plant, Cell &Environment, EarlyView.
ABSTRACT Cuticular waxes undeniably form the primary barrier restricting uncontrolled water loss from leaves, yet the functional consequences of environmentally induced wax modifications for residual (cuticular) transpiration remain a matter of debate. This review summarises current knowledge on how major abiotic stimuli influence foliar cuticular wax ...
Lena Herzig, Lukas Schreiber, Paul Grünhofer   +2 more
wiley   +1 more source

Legacy effects of livestock grazing on vegetation of an arid landscape exist more than 30 years after livestock were excluded

Restoration Ecology, EarlyView.
Abstract Introduction Globally, livestock grazing is a key driver of vegetation degradation in arid rangelands. This degradation tends to be most severe near artificial water points which are focal points for livestock activity. Conservation reserves have been established on former rangelands; however, the timeframes for vegetation recovery following ...
Neil D. Ross, Adrian Fisher, Mike Letnic
wiley   +1 more source

Optimal time of annuitization in the decumulation phase of a defined contribution pension scheme [PDF]

In this paper, we consider the problem of finding the optimal time of annuitization for a retiree of a defined contribution pension scheme having the possibility of choosing her own investment and consumption strategy.
Bjarne Højgaard, Marina Di Giacinto, Elena Vigna   +2 more
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