Results 201 to 210 of about 115,693 (341)
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
The Work Engagement Among Nurses in an Urban-Based Tertiary Hospital. [PDF]
Vimonvattana A, Benjakul N.
europepmc +1 more source
Comparisons of Early Growth between Seedlings and Sprouts, and Relationship between Original Tree Size and Vigor of Sprouts of Pusania edulis [PDF]
Satoshi Ito+2 more
openalex +1 more source
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen+4 more
wiley +1 more source
Physical Activity and Irritable Bowel Syndrome: The Role of Evolutionary Mismatch in Chronic Disease Risk. [PDF]
Lenover Moyer MB, Shenk MK.
europepmc +1 more source
Effect of Seed Weight on Emergence and Seedling Vigor of Chinese Chestnut [PDF]
Emily S. Shepard+2 more
openalex +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
This study investigates the photosensitizing potential of Passiflora cincinnata in Antimicrobial Photodynamic Therapy (aPDT) against skin infection caused by Methicillin‐resistant Staphylococcus aureus (MRSA) in a senescent murine model. The P. cincinnata exhibits antimicrobial activity, with reduced bacterial load, lower leukocyte infiltration, and ...
Caroline Vieira Gonçalves+14 more
wiley +1 more source
Chlorophyll Fluorescence, Oxygen Consumption Rates and Germination of Green Soybean Seeds Produced Under Heat-Drought Stress. [PDF]
Martinez MA+4 more
europepmc +1 more source