Results 51 to 60 of about 56,724 (289)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Irrigation management and capitulum order in the production and quality of Eryngium foetidum L. propagules [PDF]

Journal of Seed Science
: There are few recommendations for management of production and quality of propagules of Eryngium foetidum L. Thus, the aim of this study was to evaluate irrigation management during plant flowering and the harvest of different orders of inflorescences ...
Isabelle Caroline Bailosa do Rosário, Laura Monteiro Pedrosa, Giovanna de Castro, Rafaelle Fazzi Gomes, Cibele Chalita Martins   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Variabilidade de plantas de soja originadas de sementes de diferentes níveis de qualidade fisiológica

Acta Agronómica, 2015
O objetivo foi avaliar a variabilidade entre plantas dentro de populações de soja estabelecidas em sementes com diferentes níveis de qualidade fisiológica (germinação de 96, 82 e 70%, respectivamente). Foram utilizados lotes de sementes de soja, cultivar
Leandro Damero Cantarelli, Luis Osmar Braga Schuch, Lizandro Ciciliano Tavares, Cassyo de Araújo Rufino   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Vigor-S, a new system for evaluating the physiological potential of maize seeds

Scientia Agricola
: The refinement of vigor tests and the possibility of utilizing computer resources for the effective evaluation of the seed physiological potential have attracted considerable interest from research and seed technologists.
Danielle Otte Carrara Castan, Francisco Guilhien Gomes-Junior, Julio Marcos-Filho   +2 more
doaj   +1 more source

Trinexapac-ethyl as a strategy for producing seeds of oat (Avena sativa L.) cultivars [PDF]

Journal of Seed Science
: Trinexapac-ethyl (TE) is used on oat to reduce plant lodging, but little is known about its influence on seed quality. The aim of this study was to evaluate the effects of different application rates of the plant growth regulator TE on the ...
Ana Paula Silva Couto, Carlos Henrique dos Santos Fernandes, Juliana Sawada Buratto, Klever Márcio Antunes Arruda, Claudemir Zucareli, Inês Cristina de Batista Fonseca   +5 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The Vigor-S system as an auxiliary component of the accelerated aging test procedure in soybean seeds

Journal of Seed Science
: Computerized seedling image analysis is available as a resource for evaluating seed vigor or as an auxiliary component while carrying out different tests.
Gloria de Freitas Rocha Ribeiro, Abimael dos Santos Carmo-Filho, Rafael Mateus Alves, José de Barros França-Neto, Julio Marcos-Filho, Francisco Guilhien Gomes-Junior   +5 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source