Results 61 to 70 of about 115,693 (341)

Prior disinfestation of irrigated rice seeds under laboratory conditions favors expression of physiological potential

open access: yesRevista de Ciências Agroveterinárias, 2020
The purpose of this study was to analyze prior seed disinfestation of irrigated rice seeds with sodium hypochlorite and its effect on physiological quality.
Bruno Tabarelli Scheidt   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Control of movement vigor and decision making during foraging

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance How long should one stay and accumulate reward, and then, how fast should one travel to the next reward site? Marginal value theorem describes the decision-making process: the brain compares the immediate rate of harvest with its global ...
Tehrim Yoon   +3 more
semanticscholar   +1 more source

Impacts of vigorous and non-vigorous activity on daily energy expenditure [PDF]

open access: yesProceedings of the Nutrition Society, 2003
Activity intensity is a potential determinant of activity-induced energy expenditure. Tri-axial accelerometery is the most objective measurement technique for the assessment of activity intensity, in combination with doubly-labelled water for the measurement of energy expenditure under free-living conditions.
openaire   +4 more sources

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

open access: yesFEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker   +8 more
wiley   +1 more source

Reward Prediction Error Modulates Saccade Vigor

open access: yesJournal of Neuroscience, 2019
Movement vigor, defined as the reciprocal of the latency from availability of reward to its acquisition, changes with reward magnitude: movements exhibit shorter reaction time and increased velocity when they are directed toward more rewarding stimuli ...
Ehsan Sedaghat-Nejad   +2 more
semanticscholar   +1 more source

Vigorous convection in porous media [PDF]

open access: yesProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2020
The problem of convection in a fluid-saturated porous medium is reviewed with a focus on ‘vigorous’ convective flow, when the driving buoyancy forces are large relative to any dissipative forces in the system. This limit of strong convection is applicable in numerous settings in geophysics and beyond, including geothermal circulation ...
openaire   +4 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

PROTOCOL: Is the CEO/employee pay ratio related to firm performance in publicly traded companies?

open access: yesCampbell Systematic Reviews
One goal of this systematic review is to assess whether the pay ratio, that is, the relative difference between the compensation a firm's CEO receives and that of its nonmanagerial employees, is related to subsequent firm performance. A second goal is to
Denise M. Rousseau   +4 more
doaj   +1 more source

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