Results 161 to 170 of about 124,429 (359)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Teste de frio e envelhecimento acelerado na avaliação de vigor de sementes de feijão-frade Evaluation of the cowpea seeds vigour through of the coldtest and accelerated aging test

open access: yesRevista de Ciências Agrárias, 2010
Este trabalho teve como objetivo avaliar o vigor de sementes de feijão-caupi ou feijão-frade por meio dos testes de frio e de envelhecimento acelerado.
Josiane Marlle Guiscem   +7 more
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

The Effect of Traditional Shade-drying Method on Seed Germination and Vigour of Two Varieties of Tomato

open access: diamond, 2018
Olosunde Adam   +4 more
openalex   +1 more source

Accumulation of inorganic polyphosphate enables stress endurance and catalytic vigour in Pseudomonas putida KT2440 [PDF]

open access: gold, 2013
Pablo I. Nikel   +4 more
openalex   +1 more source

Transcriptomic profiling of the high-vigour maize (Zea mays L.) hybrid variety response to cold and drought stresses during seed germination

open access: gold, 2021
Heqin Li   +10 more
openalex   +1 more source

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