Results 61 to 70 of about 21,278 (265)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Molecular approach in elite parents of papaya with a focus on seed physiological quality [PDF]
Revista Brasileira de Fruticultura: Papaya seeds have natural barriers (phenolic compounds, seed structure and genetic factors) that make their germination difficult. And the use of seeds is the main means of propagating the species, whether for commercial cultivation, maintenance of ...
Fernanda Schmitt Gregolin +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2004 O ambiente mutável provoca múltiplos estresses, que podem limitar a germinação da semente e a emergência e sobrevivência da plântula. Os objetivos deste trabalho foram determinar o efeito dos estresses hídrico e salino na viabilidade e vigor de sementes ...
Silmara Cristina Fanti +1 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Ciência e Agrotecnologia, 2012 Eggplant seeds germination can be slow and uneven, justifying the use of pre-germinative treatments to improve the performance of seed lots. One option of treatment is the controlled hydration of seeds by priming.
Rodrigo de Góes Esperon Reis +4 more
doaj +1 more source
Hybrid Vigour? Genes, Genomics, and History [PDF]
Genomics, Society and Policy, 2008 Is the gene 'special' for historians? What effects, if any, has the notion of the 'gene' had on our understanding of history? Certainly, there is a widespread public and professional perception that genetics and history are or should be in dialogue with each other in some way.
openaire +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
INFLUENCE OF TEMPERATURE AND RELATIVE HUMIDITY ON GRAIN MOISTURE, GERMINATION AND VIGOUR OF THREE WHEAT CULTIVARS DURING ONE YEAR STORAGE [PDF]
Poljoprivreda, 2010 Changes in grain moisture, germination and vigour of three wheat cultivars packed in paper bags and stored for one year under four different conditions of environmental temperature and relative humidity (RH) were investigated.
Ivica Strelec +6 more
doaj