Results 61 to 70 of about 204,852 (249)

NUDIX hydrolases target specific inositol pyrophosphates and regulate phosphate homeostasis and bacterial pathogen susceptibility in Arabidopsis

Journal of Integrative Plant Biology, Volume 67, Issue 12, Page 3123-3151, December 2025.
NUDIX‐type hydrolase enzymes of subclade I and II preferentially target the inositol pyrophosphate messengers 4‐ and 3‐InsP7, respectively. Inactivation of subclade II NUDTs disrupts phosphate homeostasis and enhances bacterial resistance, revealing connections between defense and nutrient signaling.
Robin Schneider, Klea Lami, Isabel Prucker, Sara Christina Stolze, Annett Strauß, Julie Marie Schmidt, Simon M. Bartsch, Kevin Langenbach, Esther Lange, Kevin Ritter, David Furkert, Natalie Faiß, Sandeep Kumar, M. Shamim Hasan, Athanasios Makris, Lukas Krusenbaum, Stefanie Wege, Yemisrach Zewdu Belay, Simon Kriescher, Jeremy The, Michael Harings, Florian M. W. Grundler, Martina K. Ried‐Lasi, Heiko Schoof, Philipp Gaugler, Marília Kamleitner, Dorothea Fiedler, Hirofumi Nakagami, Ricardo F. H. Giehl, Thomas Lahaye, Saikat Bhattacharjee, Henning J. Jessen, Verena Gaugler, Gabriel Schaaf   +33 more
wiley   +1 more source

Late-time behaviour of the tilted Bianchi type VI$_{-1/9}$ models

, 2007
We study tilted perfect fluid cosmological models with a constant equation of state parameter in spatially homogeneous models of Bianchi type VI$_{-1/9}$ using dynamical systems methods and numerical simulations.
A A Coley, Apostolopoulos P S, Barrow J D, Coley A, Coley A A, Coley A A, Coley A A, Harnett D, Hervik S, Hervik S, Hervik S, Hervik S, Hervik S, Hewitt C G, Lim W C, R J van den Hoogen, S Hervik, W C Lim, Wainwright J   +18 more
core   +1 more source

Widely Distributed Pigeon Paramyxovirus Sub‐Genotypes Pose a Risk to Immunocompromised Humans

Zoonoses and Public Health, Volume 72, Issue 8, Page 713-724, December 2025.
ABSTRACT Introduction Pigeon paramyxovirus type 1 (PPMV‐1) is an antigenic variant of Avian Orthoavulavirus 1 (AOAV‐1) (Newcastle disease virus) with a global distribution that causes lethal infections in pigeon and dove species. AOAV‐1's infecting humans normally cause mild, self‐limiting conjunctivitis, but since 2003, PPMV‐1 has been associated with
Celia Abolnik, Michaela Hayes
wiley   +1 more source

Impact of introducing human immunodeficiency virus testing, treatment and care in a tuberculosis clinic in rural Kenya [PDF]

, 2010
SETTING: In July 2005, Médecins Sans Frontières and the Ministry of Health, Kenya, implemented an integrated tuberculosis-human immunodeficiency virus (TB-HIV) programme in western Kenya.
Guerrero, W, Huerga, H, Odongo, A, Spillane, H, Varaine, F   +4 more
core   +1 more source

Cosmological Bianchi Class A models in S\'aez-Ballester theory [PDF]

, 2011
We use the S\'aez-Ballester (SB) theory on anisotropic Bianchi Class A cosmological model, with barotropic fluid and cosmological constant, using the Hamilton or Hamilton-Jacobi approach. Contrary to claims in the specialized literature, it is shown that
Espinoza-García, Abraham, Pimentel, Luis O., Rodríguez, Paulo A., Romero, Priscila, Socorro, J.   +4 more
core   +2 more sources

HIV incidence and prevalence among adults in Mozambique: estimates from the Population‐based HIV Impact Assessment Survey (INSIDA 2021) and district‐level modelling

Journal of the International AIDS Society, Volume 28, Issue 11, November 2025.
Abstract Introduction Accurate information is needed to prioritize programmes and resources that address gaps in the HIV response. We examined findings from the 2021 Mozambique Population‐based HIV Impact Assessment (INSIDA) survey, complemented with subnational model‐based estimates of the number of new infections and district‐level incidence to gauge
Eduardo Samo Gudo, K. Carter McCabe, Erika Fazito, Daniel Catano, Orrin Tiberi, Makini Boothe, Jordan McOwen, Jeffrey W. Imai‐Eaton, Oliver Stevens, Lourena Manembe, Wafaa M. El‐Sadr   +10 more
wiley   +1 more source

HIV protease resistance mutations in patients receiving second-line antiretroviral therapy in Libreville, Gabon

BMC Infectious Diseases
Introduction In 2022, the WHO reported that 29.8 million people around the world were living with HIV (PLHIV) and receiving antiretroviral treatment (ART), including 25‌ 375 people in Gabon (54% of all those living with HIV in the country).
Guy Francis Nzengui-Nzengui, Gaël Mourembou, Hervé M’boyis-Kamdem, Ayawa Claudine Kombila-Koumavor, Angélique Ndjoyi-Mbiguino   +4 more
doaj   +1 more source

HOMA-AD, inflammation, and adipose tissue dysfunction as key drivers of immunometabolic risk in people living with HIV and type 2 diabetes

Frontiers in Endocrinology
BackgroundThe increased life expectancy of people living with HIV (PLWHIV), due to the effectiveness of antiretroviral therapy, has been associated with a higher incidence of metabolic disorders such as dyslipidemia, insulin resistance, and adipose ...
Elsa J. Anaya-Ambriz, Tania E. Holguín-Aguirre, Paula Catalina Méndez-Ríos, Monserrat Alvarez-Zavala, Monserrat Alvarez-Zavala, Luz A. González-Hernández, Luz A. González-Hernández, Jaime F. Andrade-Villanueva, Jaime F. Andrade-Villanueva, Pedro Martínez Ayala, Rodolfo I. Cabrera-Silva, Karina Sánchez-Reyes, Karina Sánchez-Reyes   +12 more
doaj   +1 more source

Infeção VIH

Revista Portuguesa de Doenças Infecciosas (RPDI), 2018
Introdução:A população com vírus de imunodeficiência humana (VIH) está a envelhecer em todo o mundo e é crescente o número de novas infeções em doentes com idade superior a 50 anos. Apesar do impacto positivo da terapêutica antirretroviral sobre morbilidade global e doenças relacionadas, estas são mais prevalentes nesta faixa etária.
openaire   +1 more source

Exploring the influence of age, gender, stigma, and years living with HIV on mental health outcomes

HIV Medicine, Volume 26, Issue 11, Page 1684-1693, November 2025.
Abstract Background People living with HIV/AIDS face a myriad of discrimination and social stigma experiences. As a result of progress observed throughout the HIV epidemic, an ageing population of people living with HIV/AIDS exists, potentially facing greater mental health challenges from combined chronic conditions and stigma.
Guilherme Welter Wendt, Lara Wiehe Chaves, Angelo Brandelli Costa   +2 more
wiley   +1 more source