Results 71 to 80 of about 11,499 (250)

CD26/DPP-4 inhibition recruits regenerative stem cells via stromal cell-derived factor-1 and beneficially influences ischaemia-reperfusion injury in mouse lung transplantation† [PDF]

, 2017
OBJECTIVES The CD26 antigen is a transmembrane glycoprotein that is constitutively expressed on activated lymphocytes and in pulmonary parenchyma. This molecule is also identified as dipeptidyl peptidase-4 (DPP-4) that cleaves a host of biologically ...
Arni, Stephan, Baerts, Lesley, De Meester, Ingrid, Jungraithmayr, Wolfgang, Matheeussen, Veerle, Weder, Walter   +5 more
core  

Relevance of indirect comparisons in the German early benefit assessment and in comparison to HTA processes in England, France and Scotland [PDF]

, 2014
Early benefit assessment in Germany under the legislative framework of AMNOG (Arzneimittelmarktneuordnungsgesetz) requires direct comparisons of the new drug with appropriate comparators determined by the Federal Joint Committee (G-BA).
Dippel, Franz-Werner, Gasche, David, Lebioda, Andrea, Plantör, Stefan, Theobald, Karlheinz   +4 more
core   +1 more source

Comparing SGLT2i and Other Oral Antidiabetic Drugs as Dual Therapy Add‐On to Metformin in Type 2 Diabetes: A Systematic Review and Meta‐Analysis

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.
This systematic literature review and meta‐analysis compared sodium‐glucose cotransporter‐2 inhibitors (SGLT‐2is) against other metformin‐containing oral dual‐therapies (ODTs) in type 2 diabetes mellitus. SGLT‐2i plus metformin exhibited overall comparable efficacy and safety, with a lower risk of hypoglycaemia and greater weight reduction than other ...
Yuhang Ma, Yi Lin, Xiaoying Ding, Yongde Peng   +3 more
wiley   +1 more source

Valsartan and Amlodipine Improved Haematological and Biochemical Indices of Vildagliptin-treated Streptozotocin-induced Diabetic Rats [PDF]

Pharmaceutical and Biomedical Research
Background: Diabetes mellitus (DM) and hypertension often coexist in sufferers, which exacerbates the complications of DM. Also, the impacts of antihypertensive medications on the treatment outcomes of DM are not fully understood.
Israel Olapeju Bolanl, Osayemwenre Erharuyi, Abigail M. Akhigbemen, Amenaghawon Imuetinyan Ugiagbe, Edobor Ekugum, Samuel O. Nwusulor, Keziah E. Adudu, Abiodun Falodun   +7 more
doaj  

Doentes com diagnóstico prévio de diabetes perdem menos peso após banda gástrica [PDF]

, 2010
[Resumo ...
Alves, Joaquim, Belo, Sandra, Carvalho, Davide, Correia, Flora, Esteves, Cesar, Freitas, Paula, Matos, Maria, Mesquita, Joana, Nogueira, Claudia, Queirós, Joana, Rodrigues, Pedro, Santos, Ana, Varela, Ana   +12 more
core  

The Level and Clinical Significance of B Lymphocytes and Immune Molecules (IL‐4, IL‐10, BAFF, and IgD) in Psoriasis

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Psoriasis is an immune‐mediated chronic skin disease. Despite the low proportion of B cells in human blood, they play an important role in regulating the pathogenesis of psoriasis. Therefore, we investigated the role and clinical significance of B cells in psoriasis by conducting experiments.
Boheng Wu, Ru Qin, Lichuan Lai, Shangyang Li, Ruilan Lin, Yunlong Zhang, Yao Guan, Yulin Yuan   +7 more
wiley   +1 more source

The efficacy of incretin therapy in patients with type 2 diabetes undergoing hemodialysis [PDF]

, 2013
BACKGROUND: Although incretin therapy is clinically available in patients with type 2 diabetes undergoing hemodialysis, no study has yet examined whether incretin therapy is capable of maintaining glycemic control in this group of patients when switched ...
Ayako Takada, Hiromasa Takenoshita, Hisahiro Nagasako, Hitoshi Nakashima, Kaoru Sugimoto, Kenji Ito, Kunitaka Murase, Nobuya Hamanoue, Ryoko Nagaishi, Satoru Ogahara, Takao Saito, Takashi Nomiyama, Toshihiko Yanase, Yasuhiro Abe, Yoko Tsutsumi, Yoshie Sasatomi, Yuichi Terawaki, Yuko Akehi   +17 more
core   +1 more source

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus

Andrology, Volume 14, Issue 3, Page 822-832, March 2026.
ABSTRACT Background Lichen sclerosus is a chronic, inflammatory, scarring disease of the skin that manifests mostly in the genital region. Objective We studied the histomorphological characteristics, grade, and pattern of inflammation in male pediatric patients with lichen sclerosus.
Valerie Flammang, Arndt Hartmann, Robert Stöhr, Katrin Weigelt, Carol Geppert, Frederik A. Stuebs, Matthias W. Beckmann, Bernd Wullich, Helge Taubert, Marios Marcou, Sven Wach   +10 more
wiley   +1 more source

Vildagliptin: a new oral treatment for type 2 diabetes mellitus

Vascular Health and Risk Management, 2008
Chantal Mathieu, Evy DegrandeDepartment of Endocrinology, Katholieke Universiteit Leuven, Leuven, BelgiumAbstract: Vildagliptin is a new oral antidiabetic agent that enhances pancreatic islet cell responsiveness to glucose.
Chantal Mathieu, Evy Degrande
doaj  

Patient preference and tolerability of a DPP-4 inhibitor a GLP-1 analog in patients with type 2 diabetes mellitus inadequately controlled with metformin: a 24-week, randomized, multicenter, crossover study

Therapeutic Advances in Endocrinology and Metabolism, 2015
Objective: The present study aimed to assess the patient preference and tolerability of oral dipeptidyl peptidase-4 inhibitor (vildagliptin) versus injectable glucagon-like peptide-1 analog (liraglutide) in patients with type 2 diabetes mellitus ...
Jörg Lüdemann, Eva D. Dütting, Markus Dworak   +2 more
doaj   +1 more source