Results 201 to 210 of about 1,644,941 (303)

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Trade-Offs of Conservation Fencing in Western Serengeti: Enhancing Agricultural Security While Navigating Unintended Consequences on Land-Use Dynamics. [PDF]

Ecol Evol
Kimaro MH, Sloots MI, Snyder KD, Mbise NL, Kakengi VA, Di Nicola W, Olff H.   +6 more
europepmc   +1 more source

High‐Performance Multi‐Walled Carbon Nanotubes‐Organic Passivated Si Solar Cells Enabled by Spatially Selective Harvesting of High‐Quality Sponges

Advanced Science, EarlyView.
Our work achieves an efficiency breakthrough in MWCNTs/Si solar cells by screening high‐quality pristine MWCNTs without any separation or purification processes. This breakthrough is mainly attributed to the excellent dispersibility of Nafion and the excellent hole transport property of MWCNTs:Nafion film containing charge transfer doping, passivation,
Yuke Ren, Qi Wang, Jiahe Chen, Jianan Zhang, Jianxin Guo, Dehua Yang, Bingbing Chen, Lu Zhang, Yiming Xu, Xuan Chang, Tiansheng Sun, Qing Gao, Anyuan Cao, Jianhui Chen   +13 more
wiley   +1 more source

Impact of the POPulation Medicine Multimorbidity Intervention in Xishui County (POPMIX) on people at high risk for COPD who smoke: protocol for the POPMIX-Smoking cluster randomised controlled trial. [PDF]

BMJ Open
Chen S, Huang K, Zheng Z, Liu Y, Zhang S, Chen W, Tang X, Cao Z, Tang L, Tong X, Zhao J, He L, Jiao L, Wang Y, Zhao T, Luo Y, Lai Q, Lyu X, Dou R, Chen Q, Bunker A, Vollmer S, Geldsetzer P, Jamison D, Bärnighausen T, Yang T, Wang C, POPMIX study investigators.   +27 more
europepmc   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Progress towards interrupting onchocerciasis transmission in the Oulibangala focus, Chad. [PDF]

Int Health
Oumar AM, Koala L, Heggen A, Ayisi F, Elaagip A, Surakat O, Atekem K, de Souza DK, Tallant J, Mackenzie CD, Otchom BB, Boakye DA.   +11 more
europepmc   +1 more source

Autonomous High‐Throughput Characterization of Liquid‐Liquid Phase Behavior

Advanced Science, EarlyView.
This study introduces an automated dual modality platform, combining asymmetric capacitance deviation and multiangle turbidimetry, for high‐throughput characterization of liquid‐liquid phase behavior across chemically diverse fluid systems. The platform enables miscibility classification, resolution of phase separation kinetics and emulsion stability ...
Tarek Eid, Maryam Ebrahimiazar, Mohammad Zargartalebi, David Sinton   +3 more
wiley   +1 more source

"It sounds unfamiliar, yet appealing": a qualitative study on perceptions of a good death and hospice care needs among older adults in remote rural China. [PDF]

BMC Palliat Care
Yu H, Song L, Wu Y.
europepmc   +1 more source

Electrically Tunable Piezotronic Transistor by Coupling Interface Polar Symmetry and Strain Gradient

Advanced Science, EarlyView.
A macroscale tip‐induced strain gradient generates bulk piezo‐charges in GaN, enabling bias‐controlled shielding and selective Schottky barrier modulation. This strain‐gradient piezotronic transistor exhibits electrically switchable high‐ and low‐sensitivity states, providing ultrahigh strain sensitivity and wide tunability for adaptive mechanical ...
Gongwei Hu, Xiaoming Dong, Yihan Zhang, Yong Chao, Menglu Li, Min Liu, Liqing Pan, Lijie Li, Wei Huang, Fobao Huang   +9 more
wiley   +1 more source

Variance partitioning reveals contrasting random effect contributions to the density and species composition of malaria-transmitting mosquitoes in western Burkina Faso. [PDF]

Parasit Vectors
Hui TJ, Epopa PS, Millogo AA, Yao FA, Koulmaga D, Noulin F, Diabate A, Burt A.   +7 more
europepmc   +1 more source