Results 31 to 40 of about 16,162 (177)

Neurofilament light chain as in vitro and clinical biomarker of vincristine‐induced peripheral neuropathy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Vincristine‐induced peripheral neuropathy (VIPN) is a common side effect in children and adolescents treated with vincristine. Assessing VIPN, especially in young children, is challenging due to a lack of sensitive tools. This limits our understanding of the nature and risk factors of VIPN. This study aimed to investigate neurofilament light chain
Peter Erik Lotko Pontoppidan   +8 more
wiley   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

open access: yesCytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook   +2 more
wiley   +1 more source

Group identities in the Central Balkan Late Neolithic

open access: yesDocumenta Praehistorica, 2012
The final period of Neolithic Vinča culture, which occupied wide areas in the Balkans, is characterised by large settlements, which were built, judging by the most recent investigations, according to premeditated plan. What was their purpose?
Adam N. Crnobrnja
doaj   +1 more source

Associations Between GLP‐1 Receptor Agonists and Alopecia: A Multi‐Centre Retrospective Analysis and Public Interest Trends

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background There is a growing body of literature suggesting that GLP‐1 receptor agonists (GLP‐1RAs) may be associated with hair loss; however, primary literature is sparse. Additionally, it is not well‐established which types of hair loss may be associated with GLP‐1RA use. Objectives This study aims to assess associations between GLP‐1RAs and
Lauren M. Ching   +2 more
wiley   +1 more source

Determination of low alloying element concentrations in cast iron by laser induced breakdown spectroscopy based on TEA CO2 laser system [PDF]

open access: yesJournal of the Serbian Chemical Society, 2017
The analytical capability of laser-produced plasma for the analysis of low alloying elements in cast iron samples has been investigated. The plasma was induced by irradiation of a sample in air at atmospheric pressure using an infrared CO2 laser ...
Savović Jelena J.   +5 more
doaj   +1 more source

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

Vinča bowls with protoma [PDF]

open access: yesStarinar, 2014
Bowls with protoma represent one of several tens of types of Vinča vessels made of baked clay which have been published as finds excavated at Vinča sites for more than a century. We are dealing here with bowls of a markedly conical profile, with
Spasić Miloš P., Crnobrnja Adam N.
doaj   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

"AN IN VITRO INVESTIGATION ON THE INHIBITORY EFFECTS OF FOUR DIFFERENT SPECIES OF VINCA EXTRACTS ON LEISHMANIA MAJOR "

open access: yesIranian Journal of Public Health, 1997
Vinca minor, Vinca major, Vinca variegata and Vinca rosea are different species of Vinca genus, of Apocynaceae family. In addition to ornamental applications, they are placed in the group of medicinal plants , because of the various alkaloids they ...
M.Assmar   +8 more
doaj  

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

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