Results 51 to 60 of about 16,162 (177)

Efficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial

American Journal of Hematology, Volume 101, Issue 7, Page 1494-1506, July 2026.
ABSTRACT Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded,
Nichola Cooper, Catherine M. Broome, Yoshitaka Miyakawa, Vickie McDonald, Hanny Al‐Samkari, Abderrahim Khelif, Spero R. Cataland, Wilma Barcellini, Renchi Yang, Heng Mei, Filip Matthijssens, Anna Hultberg, Giorgia Ciurlia, Domenica Gandini, Jaume Ayguasanosa, Kristof De Beuf, Ségolène Pastouret, Waleed Ghanima, Francesco Rodeghiero, James B. Bussel, the ADVANCE SC Investigator Trial Group, Marcela Sarmiento, Anahi Rollheiser, Hugo Ferro, Victoria Caula, Edgardo Garcia Espina, Sebastian Pastoriza, Ross I Baker, Maan Alwan, Peter Thian Guan Tan, Jir‐Ping Boey, Jack Karel Driml, Jennifer Curnow, Emily Blyth, Taryn Freeman, Amanda Johnston, John Kwan, Chun Ma, Jonathan Marwick, Kenneth Micklethwaite, Lachlin Vaughan, Zane Kaplan, Gareth Gregory, Emma Leitinger, Christopher Leow, Alexandra Murton, Jeremy Ong, Ross Salvaris, Maciej Jan Tatarczuch, Jonathan Wong, Ahmad Zargari, Michael Leahy, Philip Young‐Ill Choi, Angeline Audrey Achola Josiah, Kisoth Arasaratnam, Fathima Ayyalil, Samuel Bennett, Philip Crispin, James D’Rozario, Melanie D’Souza, Thomas Gleeson, Maya Latimer, Edwin Lee, Jun Lim, Ross Lindell‐Innes, Mridula Mokoonlall, Jun Ng, Nalini Pati, Michael Pidcock, Kristy Natasha Rady, Caitllin Thirunavukarasu, Pencho Georgiev, Maria Dimitrova, Zhanet Grudeva‐Popova, Bulent Nihat, Alexander M. Arellano Rojas, Christine M. Rojas Hopkins, Eugenia Loredo Fort, Eduardo P. Yáñez Ruiz, Mauro Leandro Morales Sanhueza, Patricio Yanez Weber, Renchi Yang, Yunfei Chen, Ting Sun, Yun Zhuang, Lei Yang, Feng Zhang, Jiajia Li, Jun Li, Lin Liu, Meng Wang, Yanli Yang, Fangbing Zhu, Junfeng Zhu, Heng Mei, Danying Liao, Quizhe Wei, Hu Zhou, Bingjie Ding, Mengjuan Li, Xuewen Song, Lina Zhang, Yuanyuan Zhang, Liang Wang, Jia Cong, Liqiang Wei, Na Yao, Hongyu Zhang, Silang Chen, Jia Feng, Lihua Sun, Haichan Xu, Lei Xu, Qian Zhang, Fengluan Zhong, Guo wei Li, Guoshu Chen, Li Chen, Xiaoyu Chen, Dongting Liu, Xiaohua Qin, Xiaoling Xie, Xiaoming Fei, D. Wenping Lu, Yilong Lu, Ming Luo, Lixia Wang, Xianqiu Yu, Xin Wang, Chao Ding, Xiaoqiong Duan, Wenhua He, Liping Huan, Yanqiu Li, Juan Liu, Ningning Tang, Wei Yin, Mamia Zodelva, Irine Datikashvili‐David, Nino Sharashenidze, Levan Makhaldiani, Teano Gamezardashvili, Ekaterine Gaprindashvili, Tamar Gersamia, Magdana Betaneli, Tamta Makharadze, Anargyros Symeonidis, Maria‐Lamprini Kasti, Alexandra Kourakli, Vasileios Lazaris, Andi Prekazi, Angelos Sarantopoulos, Marina Mantzourani, Vasiliki Antoniadou, Dimitra Vlachopoulou, Antonia Syrigou, Achilles Anagnostopoulos, Eleni Gavriilaki, Michail Iskas, Ioanna Sakellari, Christos Varelas, Ronan G. Desmond, Paraic Behan, Helen Enright, Christopher Fox, John McHugh, Grace Rothwell‐Kelly, Louisa Shackleton, Ilana Levy‐Yurkovski, Natalia Kreiniz, Sarah Matarasso‐Greenfeld, Tamar Tadmor, Anatoly Nemets, Alexander Avroutine, Yosef Barshay, Tatiana Boulygin, Shirley Zafrir‐Haver, Andrea Patriarca, Riccardo Moia, Maura Nocolosi, Wilma Barcellini, Bruno Fattizzo, Juri Giannotta, Felicetto Ferrara, Barbara Pocali, Antonio Cuneo, Maurizio Cavallari, Francesco Cavazzini, Maria Ciccone, Gian Matteo, Mariarosaria Sessa, Paolo Tomasi, Antonio Urso, Fabrizio Pane, Federico Chiurazzi, Giada Muccioli Casadei, Alessandro Lucchesi, Maria Giannini, Giovanni Marconi, Giorgia Micucci, Marianna Norata, Monica Poggiaspalla, Elena Rossi, Valerio De Stefano, Tomoki Ito, Shinya Fujita, Masaaki Hotta, Akiko Konishi, Takahisa Nakanishi, Atsushi Satake, Hideaki Yoshimura, Akio Saito, Naoki Akashi, Hirono Iriuchishima, Akira Matsumoto, Morio Matsumoto, Masahiro Mihara, Keita Nakayama, Morio Sawamura, Yukie Terasaki, Yoshitaka Miyakawa, Ryohei Abe, Atsushi Ohsaki, Kohei Saito, Rie Shiomi, Kodai Suzuki, Kento Umino, Shoko Ito, Masahiro Ashiwaza, Shinichiro Fujiwara, Kaoru Morita, Yoshinobu Kanda, Daisuke Minakata, Rui Murahashi, Hirotomo Nakashima, Ken Ohmine, Tsukasa Ohmori, Kazuya Sato, Yumiko Toda, Masuzu Ueda, Chihiro Yamamoto, Katsutoshi Ozaki, Yuya Kishida, Yasuko Kuribayashi, Keita Kirito, Eriko Hosokawa, Hideto Hyuga, Ichiro Kawashima, Megumi Koshiishi, Takuma Kumagai, Minori Matsuura, Kei Nakajima, Yuma Sakamotot, Masaru Tanaka, Takeo Yamamoto, Ryosuke Ogawa, Kenichi Aoki, Kentaro Kohno, Akihiko Numata, Teppei Obara, Yotaro Tamai, Wataru Kamata, Teiko Kawahigashi, Shuku Sato, Shun Tsunado, Shigeki Ito, Shugo Kowata, Tatsuo Oyake, Suleimman Al‐Sweedan, Dalia Alsweedan, Raghad Irshaid, Nour Sameeh, Muath Thiabat, Abdalla Awidi Abbadi, Feras Al Fararjeh, Alaa Alshorman, Jong‐Ho Won, Kyoung Ha Kim, Seug Yun Yoon, Soo‐Mee Bang, Sang‐A Kim, Jeong‐Ok Lee, Ji Yun Lee, June‐Won Cheong, Ji Eun Jang, Hyun Soo Cho, Haerim Chung, Doh Yu Hwang, Yu Ri Kim, Hyewon Kook, Yunsuk Choi, Kyoo‐Hyung Lee, Eun‐Ji Choi, Je‐Hwan Lee, Jung‐Hee Lee, Hang‐Seung Park, Mariela Cardiel Silva, Ivan Gamez Valdez, Karen Miranda Fernandez, Carlos Chavez Trillo, Alva Zaragoza Vazquez, Marco A. Velasco Rojas, Ximena Arenas Reyes, Jessica Graciela Reyes Contreras, Francisco Hernandez Rodriguez, Kirsty Marshall, Sharon Jackson, Amy J. Holmes, Peter Ganly, Andrew Butler, Wei‐Hsun Hsu, Sean Macpherson, Emma‐Jane McDonald, Wendy Stewart, Waleed Ghanima, Eiriki Tjonnfjord, Sebastian Grosicki, Ewa Bodzenta, Marek Kriegler, Zofia Spyra‐Gorny, Maria Soroka‐Wojtaszko, Oliwia Bachanek‐Mitura, Justyna Kozinska, Szymon Fornagiel, Beata Kumiega, Grzegorz Basak, Jagoda Rytel, Maciej Kazmierczak, Piotr Cieslak, Emil Durka, Marek Kotlarski, Michal Kwiatek, Justyna Pieronkiewicz, Lukasz Pruchniewski, Teresa Melo, Mafalda Alpoim, Margarida Badoir, Henrique Coelho, Cristina Fereira, Marta Nunes, Sofie Ramalheira, Antonio Medina de Almeida, Paulo Bernardo, Paula Braga, Maria Fátima Ferreira, Pedro Afonso Costa Baptista, Marta Henriques, Celina Afonso, Guadalupe Gomes, Francisca Miranda, Filipa Mousinho, Ana Ramalhal Jorge, Mariana Vasilica, Andra Tomescu, Luminita Ocroteala, Gabriela Diana Baluta, Doriana Duta, Ioan Macarie, Marcela Candea, Georgeta Daniela Georgescu, Lidia Mihai, Florina Patrinoiu, Alina Catana, Alice Dumitrescu, Gabriela Borsaru, Anca Ciobanu, Laura Cristina Predescu, Delia‐Monica Dima, Ana Maria Bancos, Daniela Dragancea, Simona Galdean, Nicoleta Negru, Sergey Zakharov, Yulia Dubinina, Alvetina Lidzhieva, Uruzmag Tomaev, I Pospelova Tatiana, Tatiana Babaeva, Olga Seregina, Svetlana A. Volkova, Elena Kiseleva, Valeria Turetskova, Maria Novikova, Zhanna Davydova, Irina Novokreschenova, Svetlana Valerievna Samarina, Marina Kokoreva, Zorica Cvetkovic, Tamara Bibic, Milica Tanasjievic, Andrew B. McDonald, David Brittain, Philippa Ashmore, Karen Gunther, Johnny Mahlangu, Ching Yu Wang, Vernon Johan Louw, Cecile Du Toit, Elzanne Jansen van Rensburg, Gerdlen Johanna Kritzinger, Perry Loebenberg, Gamuchirai Tadzimirwa, Estelle Verburgh, Blanca Sanchez Gonzalez, Sara Garcia Avila, Yao‐yu Hsieh, Yu‐Sheng Chang, Tsu‐Yi Chao, Wei‐Hong Cheng, Po‐Ya Chuang, Sheng‐Hong Lin, Hui‐Wen Liu, Archrob Khuhapinant, Rarinee Rungjirajittranon, Noppacharn Uaprasert, Chatphatai Moonla, Suporn Chuncharunee, Pichika Chantrathammachart, Teeraya Puavilai, Chatree Chai‐Adisaksopha, Pokpong Piriyakhuntorn, Tontanai Numbenjapon, Wittawat Jandamnernpong, Rattapan Lamool, Nonglak Kanitsap, Lantarima Bhoopat, Nattiya Teawtrakul, Kanchana Chansung, Theerin Lanamtieng, Chinadol Wanitpongpun, Abderrahim Khelif, Bechir Achour, Walid Bouteraa, Raihane Ben Lakhal, Yosr Abdnnebi, Dorra Dhaouadi, Emna Maaloul, Moez Elloumi, Moez Medhaffa, Selami Kocak Toprak, Bulent Karakaya, Ekin Kircali, Gul Yavuz, Filiz Vural, Nigar Abdullayeva, Aysenur Arslan, Ajda Gunes, Fatma Keklik Karadag, Tural Pashayev, Denis Sabriye Bozer, Bahar Sevgili, Nur Soyer, Tuba Hacibekiroglu, Yasin Kalpakci, Cenk Sunu, Fevzi Altuntas, Semih Basci, Merih Kizil Cakar, Sema Secilmis, Mehmet Sinan Dal, Bahar Uncu Ulu, Samet Yaman, Tugce Nur Yigenoglu, Anil Tombak, Fatma Akbas, Meliha Nalcaci, Simge Erdem, Dilek Ozden Kubilay, Tarik Tiryaki, Ozgur Mehtap, Ayfer Geduk, Meltem Ayli, Tuba Bulduk, Alparslan Merdin, Melda Ozkan, Selim Sayin, Bilge Ugur, Murat Yildirim, Ahmet Muzaffer Demir, Ufuk Demirici, Elif Umit, Ahmet Yigitbasi, Burhan Turgut, Seval Akpinar, Mehmet Sonmez, Ozlen Bektas, Nergiz Erkut, Benjamin Bailiff, Salama Abosaod, Rabia Afghan, Amy Gudger, Tsan Hei Luk, Timothy Moorby, Maria Mushkbar, Beena Salhan, Elizabeth Tebbet, Adam Forbes, Michale Creagh, Nicole Fowler, Michelle Furtado, Cristina Maria Thiebaud Alvarez, David Tucker, Martha Vickers, Nichola Cooper, Christine Ademokun, Nehal Joshi, Lucy Kamuriwo, Clare Rees, Steven Lentz, Mark Karwal, Usha Perepu, Grerk Sutamtewagul, Catherine M. Broome, Pedro Alcedo, Julia Cunningham, Graig Kessler, Sunil Babu, Farrukh Adhami, Carrie Boots, Shalini Chitneni, Ryan Gonzales, Yasolatha Nalamolu, Sreenivasa Nattam, Guinevere Nilles, Ahad Sadiq, Shelley Seabolt, David Zimmerman, Bashar Alasad, Loralei Floden, Samer Hassan, Nasser Janbay, Kellie Larsen‐Dyer, Eric S. Schaefer, Joseph Beck, Daniel Bradford, Brooke Brander, Lynsay Brautnick, Mikaila Calcagni, K’Anne Cash‐Arthur, Rita Draggs, Diane Glendinning, Cristina Hernandez, Sarah Jewell, Matthew Lockwood, Gregory Oakhill, Stephan Rosenfeld, Patrick Travis   +546 more
wiley   +1 more source

ANTIDIABETIC EFFECT OF SOME MEDICINAL PLANTS EXTRACTS [PDF]

Journal of Agricultural Chemistry and Biotechnology, 2013
          Medicinal plants play an important role in cure diseases such as diabetes mellitus. From these plants are Vinca rosea (Catharanthus roseus) and Sage (Salvia officinalis) which belong to Apocynaceae and Lamiaceae, respectively.
S. T. AboTaleb, R. A. Hassan, M. I. Sanad, Sahar E. Hamed   +3 more
doaj   +1 more source

Antioxidant and Cytotoxic Properties of Piper spp. Volatile Oils That Inhibit Pathogenic Microorganisms

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 935-942, July 2026.
The samples were fungicidal against Candida, with MICs ranging from 62.5 to 250 μg/mL, and fungistatic against Penicillium adametzii, Aspergillus flavus and A. niger, with MICs of 1000 μg/mL. The volatile oils of Piper aduncum and Piper marginatum reduced the viability of MDA‐MB231 cells.
Midiã R. Oliveira, Ely D. Alfaia Neto, Carlos Eduardo C. Alves, Renata Galvão de Azevedo, Alice F. Gomes, Flávia Juliana Reis de Sousa, Juan Campos de Oliveira, Larissa Raquel S. Maciel, Gemilson S. Pontes, Ari F. Hidalgo, Antonia Q. L. Souza, Rita C. Saraiva Nunomura   +11 more
wiley   +1 more source

In Vitro Antineoplastic Effects of Zataria multiflora: A Systematic Review of Mechanisms, Selectivity, and Synergy

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Zataria multiflora (ZM) is an aromatic plant containing various bioactive components, including phenolic compounds, flavonoids, and terpenoids. Here, we systematically review 27 articles to explore the effect of ZM on different cancer/normal cell lines.
Alireza Khanahmad, Fatemeh Peymaninezhad, Fariba Sharififar, Ali Sadatmoosavi, Ali Bazi, Roohollah Mirzaee Khalilabadi, Hajar Mardani Valandani   +6 more
wiley   +1 more source

HURP binding to the vinca domain of β-tubulin accounts for cancer drug resistance

Nature Communications
Vinca alkaloids, a class of tubulin-binding agent, are widely used in treating cancer, yet the emerging resistance compromises their efficacy. Hepatoma up-regulated protein (HURP), a microtubule-associated protein displaying heightened expression across ...
Athira Saju, Po-Pang Chen, Tzu-Han Weng, Su-Yi Tsai, Akihiro Tanaka, Yu-Ting Tseng, Chih-Chia Chang, Chun-Hsiung Wang, Yuta Shimamoto, Kuo-Chiang Hsia   +9 more
doaj   +1 more source

Ab initio study of graphene interaction with O2, O and O-

Macedonian Journal of Chemistry and Chemical Engineering, 2016
A systematic ab initio (DFT-GGA) study of adsorption of various oxygen species on graphene has been performed in order to find out general trends and provide a good starting point to analyze the oxidation of more complex carbon materials.
Dragana Vasic Anicijevic, Ivana Perovic, Sladjana Maslovara, Snezana Brkovic, Dragana Zugic, Zoran Lausevic, Milica Marceta Kaninski   +6 more
doaj   +1 more source

THE ANTIMICROBIAL EFFECT OF GENUS VINCA ON SOME PATHOGEN MICROORGANISM

Iranian Journal of Public Health, 1995
Vinca major, minor and rosea are three species of vinca genus and Apocynaceae family. The present work is to investigate antimicrobial effects of these plants against Candida albicans, Pseudomonas aeroginosa and Staphylococus aureus.
S.Mehrab, A. Majd, T. Tamadon   +2 more
doaj  

Effects of gamma-radiation on cell growth, cycle arrest, death, and superoxide dismutase expression by DU 145 human prostate cancer cells

Brazilian Journal of Medical and Biological Research, 2006
Gamma-irradiation (gamma-IR) is extensively used in the treatment of hormone-resistant prostate carcinoma. The objective of the present study was to investigate the effects of 60Co gamma-IR on the growth, cell cycle arrest and cell death of the human ...
V. Vucic, E.R. Isenovic, M. Adzic, S. Ruzdijic, M.B. Radojcic   +4 more
doaj   +1 more source

External Evaluation of Population Pharmacokinetic Models of Cabotegravir, During Its Oral and Intramuscular Administration in HIV‐Infected Patients

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Cabotegravir (CAB), combined with rilpivirine, is the first long‐acting injectable therapy approved for HIV‐1 maintenance treatment. While adherence and patient satisfaction have been improved, pharmacokinetic (PK) variability remains a concern.
Quentin Renou, Nadège Néant, Alexandre Destere, Jennifer Lagoutte‐Renosi, Matthieu Grégoire, François Parant, Sébastien Lalanne, Florian Lemaitre, Peggy Gandia, Nicolas Venisse, Stéphane Bouchet, Minh P. Lê, Patrice Muret, Gilles Peytavin, Caroline Solas, Sihem Benaboud, the CARLA Study Group, Benoît Bailly, Vincent Gendrin, Timothhee Klopenstein, Souheil Zayet, Quentin Lepiller, Fabienne Bozon, Anne‐Sophie Brunel, Bruno Hoen, Laurent Hustache‐Mathieu, Camille Tumiotto, Mojgane Hemssamfar, Fabrice Bonnet, Ali Si‐Mohammed, Lionel Piroth, Marielle Buisson, Sophie Mahy, Michel Duong, Vinca Icard, Mary‐Anne Trabaud, Dulce Alfaiate, Agathe Becker, Evelyne Braun, Florence Brunel, Matthieu Godinot, Thomas Perpoint, Clément Javaux, Céline Boschi, Philippe Colson, Anne Motte, Véronique Obry‐Roguet, Sylvie Brégigeon, Olivia Faucher‐Zaegel, Hélène Laroche, Maeva Dos Santos, Isabelle Ravaux, Catherine Dhiver, Christelle Tomei, Amélie Ménard, Matthieu Million, Patrick Philibert, Christina Psomas, Jakub Kowalczyk, Simona‐Loredana Berbescu, Catherine Michel, Elisabeth André‐Garnier, Thomas Drumel, Clotilde Allavena, Eric Billaud, Sabelline Bouchez, Cécile Brunet‐Cartier, Colin Deschanvres, François Raffi, Véronique Reliquet, Gwennaelle Querne, Cecile Mear‐Passard, Antoine Asquier, Charlotte Moyon, Virginie Beslon, Lio Collias, Anne‐Geneviève Marcelin, Vincent Calvez, Diane Descamps, Valentine Ferré, Yazdanpanah Yazdan, Jade Ghosn, Valérie Pourcher, Marc‐Antoine Valantin, Gwenaël Le Moal, David Plainchamp, Anne Maillard, François Benezit, Cédric Arvieux, Pierre Gantner, Christine Cheneau, Axel Ursenbach, Baptiste Hoellinger, Céline Melounou, David Rey, Yves Hansmann   +95 more
wiley   +1 more source

Contrasting direct and indirect effects of roe deer on herb layer vegetation in gaps and closed canopies

Journal of Ecology, Volume 114, Issue 6, June 2026.
Forest gaps primarily reshape herb layer composition by increasing light availability and shrub layer encroachment. Roe deer influence herb layer community assembly both directly and indirectly via modification of the shrub layer and light availability and thus shifting plant–plant competition.
Ludwig Lettenmaier, Marc W. Cadotte, Sebastian Dittrich, Kerstin Pierick, Christian Ammer, Pia M. Bradler, Simone Cesarz, Nico Eisenhauer, Andreas Fichtner, Daniel Kraus, Soumen Mallick, Atle Mysterud, Goddert von Oheimb, Christian Ristok, Jörg Müller   +14 more
wiley   +1 more source