Results 171 to 180 of about 70,411 (245)

Artificial cell vesicle-mediated delivery of <i>Catharanthus roseus</i> (L.) G. Don-derived vinca alkaloids for enhanced antitumor efficacy. [PDF]

Front Bioeng Biotechnol
Zhuang X, Huang L, Liu R, Guan L, Fang X, Ma T.   +5 more
europepmc   +1 more source

Mitochondrial Transfer in the Tumor Microenvironment

Cancer Science, Volume 117, Issue 5, Page 1189-1198, May 2026.
Mitochondria are actively exchanged among tumor, immune, stromal, and neuronal cells within the tumor microenvironment. Such transfer rewires tumor metabolism, promotes immune evasion, and drives therapy resistance. Targeting mitochondrial transfer or harnessing mitochondrial transplantation represents a promising strategy to restore antitumor immunity
Ryo Omae, Takamasa Ishino, Yosuke Togashi   +2 more
wiley   +1 more source

Probiotic-enhanced chemotherapy: Lactobacillus fermentum synergizes with vincristine to induce apoptosis via dual pathway activation in human cancer cells. [PDF]

Cancer Cell Int
Asoudeh-Fard A, Asoudeh-Fard M, Parsaei A.   +2 more
europepmc   +1 more source

Frontline Therapy in Diffuse Large B‐Cell Lymphoma: Evolving Standards, Biological Insights, and Future Directions

European Journal of Haematology, Volume 116, Issue 5, Page 522-534, May 2026.
ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) remains the most common aggressive lymphoma, representing a biologically heterogeneous disease with diverse clinical behaviors. For more than two decades, R‐CHOP has been the cornerstone of frontline treatment, curing approximately two‐thirds of patients.
Mamdouh Skafi, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Fortunato Morabito, Enrica Antonia Martino, Massimo Gentile   +12 more
wiley   +1 more source

Correspondance: Venetoclax combined with FLAG-based chemotherapy induces rapid and deep responses in early T-cell precursor lymphoblastic leukemia/lymphoma. Report of two cases and review of the literature. [PDF]

Ann Hematol
Dereme J, Segot A, Nabergoj M, Dewarrat N, Basset V, Blum S, Tsilimidos G.   +6 more
europepmc   +1 more source

Exosomal Non‐Coding RNAs in Gastrointestinal Cancer Drug Resistance: A Systematic Review of Emerging Mechanisms and Clinical Implications

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak, Zahra Sadeghloo, Fateme Binayi, Stefania Nobili, Sara Ashtari, Amir Sadeghi, Nayeralsadat Fatemi   +6 more
wiley   +1 more source

Hereditary Bilateral Retinoblastoma Detected on Screening in a Two-Month-Old Infant With a Strong Family History. [PDF]

Cureus
Bhola DE, Bhola RM, Dindial K.
europepmc   +1 more source

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 3, Page 237-256, May 2026.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

ELDA: real-time functional drug profiling in acute lymphoblastic leukemia. [PDF]

Front Oncol
Mariano SS, Assis LHP, Correa JR, Canevarolo RR, Migita NA, Sudalagunta PR, de Azevedo AC, Meidanis J, Brandalise SR, Silva AS, Yunes JA.   +10 more
europepmc   +1 more source

Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma. [PDF]

iScience
Kolodziejczak AS, Selt F, Peterziel H, Jamaladdin N, Mack N, Maaß K, Meulenbroeks C, Sigaud R, Herold-Mende C, El Damaty A, Burhenne J, Ohmura S, Holland-Letz T, Kutscher LM, Ernst A, Wei PC, Grünewald TGP, Oehme I, Kool M, Jones DTW, Pajtler KW, Kratz CP, Pfister SM, Witt O, Milde T.   +24 more
europepmc   +1 more source