Results 161 to 170 of about 71,769 (253)

The impact of whole lung irradiation in lung metastatic rhabdomyosarcoma: A pooled analysis of two European trials and one European registry

open access: yesCancer, Volume 132, Issue 15, 1 August 2026.
ABSTRACT Background Lung metastases in patients with metastatic rhabdomyosarcoma (RMS) have not been treated uniformly across Europe. This provides comparison of the impact of whole lung irradiation (WLI). Methods Lung‐metastatic patients included in the Cooperative Weichteilsarkom Studiengruppe‐IV 2002, European Pediatric Soft Tissue Sarcoma Study ...
Amadeus T. Heinz   +14 more
wiley   +1 more source

Acute and Chronic Leukemia in Sub‐Saharan Africa: A Systematic Review

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background The four primary subgroups of leukemia include chronic myeloid leukemia (CML), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), and chronic lymphocytic leukemia (CLL). Very little is known about the regional variation of leukemia and subtypes in sub‐Saharan Africa (SSA).
Allwell A. Ayirebi   +17 more
wiley   +1 more source

Safety and Effectiveness of Denileukin Diftitox‐cxdl in Patients With Relapsed/Refractory Peripheral T‐Cell Lymphoma and Cutaneous T‐Cell Lymphoma: An All‐Case Post‐Marketing Study in Japan

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Introduction Denileukin diftitox (DD)‐cxdl, a fusion protein comprising diphtheria toxin fragments and human interleukin‐2, is a treatment for peripheral T‐cell lymphoma (PTCL) and cutaneous T‐cell lymphoma (CTCL). Previous trials have enrolled a limited number of patients, and there is a need to evaluate DD‐cxdl in a more diverse population ...
Tatsuro Jo   +3 more
wiley   +1 more source

Efficacy of Nivolumab in Chemotherapy‐Resistant Mesothelioma of the Tunica Vaginalis Testis: A Case Report

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Mesothelioma of the tunica vaginalis testis is a rare neoplasm, accounting for less than 1% of all mesothelioma cases. Due to the rarity of this disease, a standard treatment has not been established. Clinical management is generally adapted from the strategies used for pleural mesothelioma.
Haruki Koyanagi   +17 more
wiley   +1 more source

Dissecting diffuse large B‐cell lymphoma heterogeneity: New insights from a state‐specific molecular characterisation

open access: yesClinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Integrating DNA and RNA sequencing with digital deconvolution, this study identifies five malignant B‐cell states in DLBCL with distinct mutational and microenvironmental profiles. These states predict survival independently of standard indices, revealing a critical dichotomy between favourable TME‐dependent (S1) and aggressive TME‐independent (S5 ...
Robel Papotti   +22 more
wiley   +1 more source

Response to the Letter to the Editor Entitled "Revisiting Vincristine for FSGS: Proof-of-Mechanism Arrives, but Whom Should we Treat?" [PDF]

open access: yesKidney Int Rep
Mason WJ   +11 more
europepmc   +1 more source

Precision post‐translational modification of PML defines neuroblastoma clinical behaviour

open access: yesClinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Promyelocytic leukaemia protein (PML) loss is significantly associated with advanced disease stage, metastasis, relapse, therapy resistance, and poor survival in neuroblastoma. Elevated phosphorylation of PML at S518 promotes PML destabilisation and predicts adverse clinical outcomes. The phosphorylated PML (pPML)/PML ratio provides enhanced prognostic
Sreenidhi Mohanvelu   +6 more
wiley   +1 more source

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