Exploring Resistance to ETS Targeting Agents in Diffuse Large B‐Cell Lymphoma
Cancer Medicine, Volume 15, Issue 5, May 2026.This study provides the first systematic characterization of resistance to ETS inhibition in diffuse large B‐cell lymphoma (DLBCL). Using TK216‐resistant models, we reveal heterogeneous escape mechanisms, including MDR1 upregulation, transcriptional reprogramming, and cytoskeletal remodeling, each associated with distinct mutational signatures ...
Filippo Spriano +9 more
wiley +1 more source
Perianal Rhabdomyosarcoma Mimicking Perianal Abscess: Case Report and Literature Review. [PDF]
Case Rep OncolShamohammadi M +5 more
europepmc +1 more source
Aggressive Desmoplastic Small Round Cell Tumor in an Adult: A Case Report and Literature Review
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive sarcoma that predominantly affects adolescents and young adults. It is defined by a characteristic chromosomal translocation, t(11;22) (p13;q12), resulting in the EWS–WT1 fusion gene.
Seyed Amir Aledavood +4 more
wiley +1 more source
Secondary primary malignancies in indolent non-Hodgkin lymphoma patients receiving frontline bendamustine-rituximab. [PDF]
CancerDavies GA +7 more
europepmc +1 more source
Primary Cardiac Lymphoma: A Diagnostically Challenging Case Report
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT This case highlights the diagnostic difficulties of PCL, including non‐specific symptoms, imaging mimics, and the critical role of histopathological confirmation despite technical and clinical challenges. Early multidisciplinary evaluation is essential to improve outcomes in this aggressive disease.
Yucheng Huang +6 more
wiley +1 more source
B-Cell Lymphoma Following an Indolent Course Over 30 Years with Immunophenotypic Changes at Each Recurrence. [PDF]
Eur J Case Rep Intern MedYamanaka S +6 more
europepmc +1 more source
Malignant Proliferating Trichilemmal Tumor: A Rare Case Report and Review of Literature
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT This case shows the rarity of Malignant Proliferating Trichilemmal Tumor (MPTT) as well as its aggressive behavior as an adnexal tumor with metastatic potential, requiring early diagnosis and excision. MPTT may occur in younger patients and at atypical sites; malignant transformation should be suspected in long‐standing trichilemmal lesions ...
Chanda Shrestha +5 more
wiley +1 more source
Real-world outcome and dose intensity of Pola-R-CHP versus R-CHOP/R-THP-COP in newly diagnosed diffuse large B-cell lymphoma: a single-center, retrospective cohort study. [PDF]
BMC CancerFujita K +7 more
europepmc +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT The central nervous system (CNS) is the most common site of extramedullary relapse in acute lymphoblastic leukemia (ALL). However, the diagnosis may be challenging due to its protean manifestations. A 64‐year‐old male reported right‐sided hearing loss with intermittent bilateral occipitotemporal headaches during a clinic follow‐up for Ph + B ...
Jun Yen Ng +3 more
wiley +1 more source
Clinicopathological Characteristics and Outcomes of Genitourinary Rhabdomyosarcoma in Two Girls
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT Rhabdomyosarcoma (RMS) is a soft tissue neoplasm accounting for about 8% of solid tumors in children. There are mainly four histologic subtypes of RMS: embryonal, alveolar, spindle cell/sclerosing, and pleomorphic. The genitourinary tract is the second most affected primary site of RMS. Genitourinary RMS is more common in young boys than girls.
George Evele +3 more
wiley +1 more source