Results 131 to 140 of about 71,512 (251)

Human iPSC-Derived Dorsal Root Ganglion Organoid Modeling of Chemotherapy-Induced Peripheral Neuropathy. [PDF]

Cells
Hrstka SCL, Jahnke M, Meng-Lin K, Lindorfer S, Noma H, Hrstka RF, Staff NP.   +6 more
europepmc   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1760-1770, June 2026.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source

Chemotherapy-induced oxidative injury in pediatric acute lymphoblastic leukemia: The role of N-acetylcysteine (Review). [PDF]

Biomed Rep
Soetadji RS, Soetadji S, Jonathan T, Sanjaya A.   +3 more
europepmc   +1 more source

Metastatic Ewing Sarcoma, Patterns of Care and Outcomes of Patients in a Real‐Life National Setting Over a Decade

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Metastatic Ewing sarcoma (MES) has a poor prognosis. This multicenter observational study provides real‐world data on treatment patterns of patients with MES in France. Treatment characteristics, outcomes such as time to next treatment (TTNT) and overall survival (OS), and prognostic factors of patients aged ≥ 12 years treated for a MES in 11 ...
Coline Ducrot, Derek Dinart, Maeva Bonneau, Max Piffoux, Marie Sophie Minot, Juliane Mignot‐Posson, Thomas Grinda, Jordane Chaix, Sarah Winter, Pauline Gerard, Romain Duong, Berengère Narciso, Natacha Entze Werle, Cécile Vérité, Valérie Laurence, Axel Le Cesne, Pablo Berlanga, Camille Tlemsani, Pascaline Boudou‐Rouquette, Emmanuelle Bompas, Thibaud Valentin, Nadège Corradini, Mehdi Brahmi, Carine Bellera, Maud Toulmonde   +24 more
wiley   +1 more source

Optimizing first-line therapy for double-expressor lymphoma: a systematic review and meta-analysis of novel agent-augmented R-CHOP regimens. [PDF]

Cancer Cell Int
Zhang MY, Xiao F, Li ZH, Huang HH.
europepmc   +1 more source

New Insights Into the Role of Neutrophils in Lymphoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
Tissue‐resident neutrophils challenge conventional paradigms by actively infiltrating normal lymphoid organs, predominantly localizing in interstitial compartments, a spatial distribution distinct from their classical vascular positioning. Neutrophils in lymphoid organs exhibit unique phenotypic and functional signatures, suggesting they play roles in ...
Ling Gu
wiley   +1 more source

A systematic evaluation of double-expressor lymphoma: prognostic impact, determinants of outcome, and comparative efficacy and safety of novel therapies. [PDF]

Front Oncol
Guan H, Liu Z, Gao C, Wang W, Liu K, Zhao X.   +5 more
europepmc   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Anti‐Inflammatory Potential of Key Phytochemicals From Humboldtia sanjappae: In Vivo Studies and Molecular Docking With MM‐GBSA Analysis

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Humboldtia sanjappae bark extract evaluated for its anti‐inflammatory potential using in vivo paw edema models and in silico molecular docking. Bioactive flavonoids, particularly neoeriocitrin, showed strong interactions with TNF‐α, COX‐2, IL‐6, and IL‐1β, highlighting the extract's multi‐target anti‐inflammatory activity and therapeutic promise ...
Jameema Sidhic, Madhu Tanya Singh, Sruthi Mohan C. K., Aparna Prasad, Paromita Sarbadhikary, Praveen Thaggikuppe Krishnamurthy, Sulaiman C. T., Arunaksharan Narayanankutty, Heidi Abrahamse, Satheesh George, Blassan P. George   +10 more
wiley   +1 more source

Case Report: Vincristine-induced acute pancreatitis in pediatric Wilms tumor: first reported case challenging previous risk classifications and proposing vigilant monitoring protocols. [PDF]

Front Pediatr
Liu T, Cao Z, Lai F, Xu H, Chen Z, Yuan X, Liu X.   +6 more
europepmc   +1 more source