Results 111 to 120 of about 71,769 (253)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise   +2 more
wiley   +1 more source

Dynamic changes in thiol–disulfide homeostasis and oxidative stress during vincristine treatment in Kangal bitches with transmissible venereal tumor

open access: yesRevista Científica
The aim of this study was to evaluate time-dependent changes in oxidative stress biomarkers and thiol-disulfide homeostasis in dogs diagnosed with canine transmissible venereal tumor and treated with vincristine sulfate. Eighteen female Kangal dogs were
Murat Can Demir   +6 more
doaj  

Integrated Phytochemical Characterisation, Pharmacological Evaluation and Computational Investigation of Acampe papillosa Stem Extract

open access: yesAnalytical Science Advances, Volume 7, Issue 2, December 2026.
The pharmacological potential of the methanolic stem extract of Acampe papillosa is evaluated using in vivo and in silico approaches. The extract demonstrates significant anxiolytic, sedative, anti‐inflammatory, and antipyretic activities in experimental models, while molecular docking supports the observed biological effects through favorable ...
Qurratul Ain Sadia   +10 more
wiley   +1 more source

QW-5-70 targets the colchicine site and demonstrates antitumor activity in P-gp-overexpressing cancer models. [PDF]

open access: yesMol Cancer Ther
Xie Y   +11 more
europepmc   +1 more source

Therapeutic Exercise Protocol During Hospitalization in Pediatric Oncohematological Patients: Randomized Clinical Trial

open access: yesPhysiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Background Leukemias, lymphomas, and central nervous system tumors are among the most common pediatric cancers and may lead to motor deficits, impaired balance, reduced muscle strength, fatigue, and decreased functional capacity. Early physiotherapy during hospitalization may help prevent inactivity and support functional preservation in this ...
Cintia Freire Carniel   +4 more
wiley   +1 more source

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