High intratumor heterogeneity in DLBCL is associated with reduced event‐free survival, particularly in the ABC subtype. Tumors with high clonal composition exhibit more aggressive biological behavior compared to monoclonal tumors in the ABC subtype of DLBCL.
Takahiro Haeno +8 more
wiley +1 more source
Probiotic-enhanced chemotherapy: Lactobacillus fermentum synergizes with vincristine to induce apoptosis via dual pathway activation in human cancer cells. [PDF]
Asoudeh-Fard A +2 more
europepmc +1 more source
Two Cases of External Ophthalmoplegia after Vincristine Treatment in Childhood [PDF]
Dong Hyun Lee, Jae Ho Jung
openalex +1 more source
ABSTRACT This case report highlights that Langerhans cell histiocytosis should be suspected in the differential diagnosis for children who exhibit failure to thrive, diabetes insipidus, and skin lesions. Early recognition and timely management are crucial for preventing irreversible hypothalamic–pituitary damage and improving outcomes.
Kidus Geabriel Yohannes +3 more
wiley +1 more source
Artificial cell vesicle-mediated delivery of <i>Catharanthus roseus</i> (L.) G. Don-derived vinca alkaloids for enhanced antitumor efficacy. [PDF]
Zhuang X +5 more
europepmc +1 more source
Fourteen-day rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP-14): use it right or do not use it at all [PDF]
Carsten Zwick, Michael Pfreundschuh
openalex +1 more source
DNTTIP1 drives leukaemogenesis through MiDAC‐mediated epigenetic silencing of BMF
DNTTIP1 cooperates with SP1 to recruit HDAC1/2, leading to BMF silencing and reduced competitive binding of BMF to BCL2.This suppresses autophagy and apoptosis, promoting leukaemic cell survival. Targeting the DNTTIP1‐HDAC1/2‐BMF axis reactivates BMF and induces anti‐leukaemic effects.
Ruolin Xiu +12 more
wiley +1 more source
Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma. [PDF]
Kolodziejczak AS +24 more
europepmc +1 more source
Chemotherapy of disseminated melanoma with bleomycin, vincristine, CCNU, and DTIC (BOLD regimen) [PDF]
Eduardo L. Franco
openalex +1 more source
New cell lines expanding the diversity of Ewing sarcoma models
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff +13 more
wiley +1 more source

