Results 81 to 90 of about 86,503 (159)

List of genes differentially regulated between vincristine-morphine vs. vincristine-oxycodone treated animals.

, 2014
Data are illustrated as follows: 1) Gene accession number; 2) Gene symbol; 3) Mean expression of the genes for the six different groups; 4) results of variance analysis between vincristine and control: p-value; 5) results of Student's t-test between ...
Bernard Calvino (533496), Fabien Marchand (533497), Stephen B. McMahon (108989), Sophie Pezet (533499), Karine Thibault (533495), Isabelle Rivals (144406), Sophie Dubacq (533498)   +6 more
core   +1 more source

Effects of vincristine on the properties of low threshold mechanoreceptors and high threshold mechanoreceptors in the hindpaw glabrous skin of mice

Molecular Brain
Vincristine is an important chemotherapy drug to treat various types of cancer, but it induces peripheral neuropathy, leading to numbness and mechanical allodynia in the hands and feet of patients. The peripheral neuropathy is a dose-limiting toxicity of
Akihiro Yamada, Ayaka I. Yamada, Jennifer Ling, Jianguo G. Gu   +3 more
doaj   +1 more source

Andrographolide promotes vincristine-induced SK-NEP-1 tumor cell death via PI3K-AKT-p53 signaling pathway

, 2016
Mingsheng Zhang, Enda Xue, Wei Shao Department of Pediatric Surgery, Liaocheng People’s Hospital, Liaocheng, Shandong Province, People’s Republic of China Background: Nephroblastoma (Wilms’ tumor [WT]) is the most common malignant ...
Xue E, Shao W, Zhang M
core  

PDH Inhibition in Drosophila Ameliorates Sensory Dysfunction Induced by Vincristine Treatment in the Chemotherapy-Induced Peripheral Neuropathy Models

Biomedicines
Background/Objectives: Chemotherapy-induced peripheral neuropathy (CIPN) is a significant dose-limiting side effect of many effective anticancer agents, including vincristine. While CIPN adversely affects both oncological outcomes and the quality of life
Harim Song, Sohee Kim, Ji Eun Han, Kyong-hwa Kang, Hyongjong Koh   +4 more
doaj   +1 more source

Vincristine Therapy of Idiopathic and Secondary Thrombocytopenias

, 1974
Idiopathic thrombocytopenia refractory to glucocorticoids and splenectomy remains a serious problem. Prompt benefit was obtained from vincristine in six of seven patients not splenectomized who were refractory to glucocorticoids and in nine of 13 ...
Seelman, Robert C, Ahn, Yeon S, Charles S. Eytel, William J. Harrington, Harrington, William J, Robert C. Seelman, Eytel, Charles S, Yeon S. Ahn   +7 more
core   +1 more source

Review of abiotic and biotic elicitors’ roles in secondary metabolites biosynthesis of periwinkle (Catharanthus roseus (Linn.) G. Don)

Journal of Medicinal Plants, 2020
Background: Based on recent statistical survey, the cancer is the third important factor in Iran mortality. Vinblastine and vincristine alkaloids are dominantly biosynthesized in the aerial parts of periwinkle, broadly applied for cancer treatment ...
Saleh Amiri, Reza Fotovat, Bahman Panahi, Alireza Tarinezhad, Seyyed Abolghasem Mohammadi   +4 more
doaj  

Isolated abducens nerve palsy induced by vincristine therapy

, 2004
We report a 28-year-old man with non-Hodgkin's lymphoma who presented with acute onset of diplopia 3 weeks after the completion of combination chemotherapy with vincristine. He had a left esotropia with marked decrease in abduction.

core   +1 more source

Neurotoxicity of vincristine on the medial olivocochlear bundle

, 2007
Objective: Vincristine is a well known neurotoxic chemotherapeutic agent. Dose dependent and cumulative peripheral neuropathy is the main dose limiting side effect of chemotherapy with vincristine. The mechanisms responsible for the neurotoxic effects of
Psarommatis, I., Varvutsi, M., Riga, M., Giotakis, I., Ferekidis, E., Korres, S., Apostolopoulos, N.   +6 more
core   +1 more source

Treatment of cervical carcinoma with methotrexate, bleomycin and vincristine.

, 1981
Seventeen patients with squamous cell carcinoma of the cervix received a combination of methotrexate, bleomycin, and vincristine. Oral methotrexate and parenteral bleomycin were given every week and intravenous vincristine was given every other week ...
Lee, J H, Behnam, K, Looka, M H, Lewis, G C   +3 more
core   +1 more source

MAPK-driven MYC/p21 axis controls senescence bypass and BCL-XL dependence in vincristine-resistant rhabdomyosarcoma. [PDF]

iScience
Wang Y, Largent AD, Lee D, Modi P, Wang L, Bandhlish A, Ignatius M, Chen EY.   +7 more
europepmc   +1 more source