Results 81 to 90 of about 114,903 (176)

Catalytic asymmetric synthesis of 3,2'-pyrrolinyl spirooxindoles via conjugate addition/Schmidt-type rearrangement of vinyl azides and (E)-alkenyloxindoles. [PDF]

Chem Sci, 2020
Zhong Z, Xiao Z, Liu X, Cao W, Feng X.
europepmc   +1 more source

Synthese und aktivitätsbasierte Proteinprofilierung identifizieren die Aldo‐Keto‐Reduktase 1C3 als Zielprotein der Myxoglucamide

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, Volume 65, Issue 41, 5 October 2026.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Copper(i)-mediated carboamination of vinyl azides by aryldiazonium salts: synthesis of N²-substituted 1,2,3-triazoles

, 2017
Copper(i)-mediated carboamination reaction of vinyl azides with sole aryldiazonium salt for N2-substituted 1,2,3-triazoles.
Wen Gao, Guangyu Zhu, Zhenhua Liu, Bo Tang, Huimin Ji, Fengcai Lei, Lili Tong   +6 more
core   +1 more source

Reactivities of vinyl azides and their recent applications in nitrogen heterocycle synthesis. [PDF]

Org Biomol Chem, 2015
Hu B, DiMagno SG.
europepmc   +1 more source

Visible-light sensitization of vinyl azides by transition-metal photocatalysis. [PDF]

Angew Chem Int Ed Engl, 2014
Farney EP, Yoon TP.
europepmc   +1 more source

Telescoped Flow Synthesis of Azacyclic Scaffolds Exploiting the Chromoselective Photolysis of Vinyl Azides and Azirines. [PDF]

Chemistry
Crawford R, Baumann M.
europepmc   +1 more source

Mn(III)-catalyzed synthesis of pyrroles from vinyl azides and B-keto acids.

, 2010
β-keto acids and vinyl azides are found to be promising precursors for the synthesis of pyrroles with Mn(acac)3 as a catalyst. One electron oxidation of β-keto acids by Mn(acac)3 induces decarboxylation to afford α-keto radicals, which then add on to ...
Ng, Eileen Pei Jian.
core  

Kinetically Stable Boron-Heteroatom Bonds. [PDF]

Angew Chem Int Ed Engl
Trofimova A, Huang BZ, Soor HS, White B, Holownia A, Lebedev Y, Lough AJ, Dudding T, Yudin AK.   +8 more
europepmc   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles' Biointerface to Advance Precision Therapeutics. [PDF]

Adv Mater
Pourtalebi Jahromi L, Geng F, Frenzke JN, Fuhrmann G.   +3 more
europepmc   +1 more source