Results 31 to 40 of about 56,532 (299)
CHIMIA, 2012 Mn(iii)-catalyzed formal [3+2]- and [3+3]-annulations have been developed using readily available vinyl azides with 1,3-dicarbonyl compounds and cyclopropanols.
Shunsuke Chiba
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Vinyl sulfones: selective and tunable covalent warheads against challenging enzyme targets [PDF]
Exploration of Drug ScienceOver the past several decades there has been a growing recognition of the role that covalent drug candidates have played in the drug development process. With this recognition, compounds that are capable of selectively and irreversibly inactivating their
Ronald E. Viola
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Polymerization of Vinyl Compounds by the Sodium-adducts of Heterocyclic Vinyl Compounds
Nippon kagaku zassi, 1960 側鎖にビニル基をもった複素環式化合物すなわちビニルピリジン,ビニルフラン,ビニルチオフェン等の金属ナトリウムとの付加化合物の合成を行ない,これらの付加化合物による数種のビニル化合物の重合反応を試みた結果,いずれの付加化合物も求電子的官能基をもつビニル化合物に対してはいちじるしい重合触媒活性を有するが,求核的官能基をもつビニル化合物に対しては共役系ビニル化合物についてのみ触煤活性が認められ,しかもこの触媒活性は付加化合物の種類によって異なることが認められた。一方付加化合物の電子スピン共鳴吸収,近紫外部吸収スペクトルの測定結果から推定される付加化合物の構造はラジカルアニオンであるが,低温では付加化合物からビニル化合物への電子移動によるアニオン重合が支配的であると考えると ...
Keiji KUWATA +2 more
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Phosphoranaloga von Aminosäuren und Peptiden: Kettenverlängerung von Carbonylverbindungen
CHIMIA, 1982 Synthesis of carbonyl compounds 5 involving the Wittig-Horner reaction of diethyl-1-isocyanoalkylphosphonate 1 with carbonyl compounds 2 and subsequent hydrolysis of the vinyl isocyanides 3 formed is reported.
Janusz Rachoń
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Oxycyanation of Vinyl Compounds
The Journal of the Society of Chemical Industry, Japan, 1971 イソプチレン, スチレン, 塩化ビニル, アクリロニトリルならびにベンゼンのナキシシアン化反応を行なった。イソブチレンからはβ,β-ジメチルアクリロニトリルが生成した。イソブチレンのオキシシアン化反応の動力学的挙動はエチレンに似ている。スチレンからは cis-β-ならびに trans-β-フェニルアクリロニトリルが生成した。塩化ビニルからはα-, cis-β- ならびに trans-β-クロロアクリロニトリルが得られた。β-クロロアクリロニトリルより逐次的にフマロニトリルが生成した。アクリロニトリルのオキシシアン化によりフマロニトリルが得られたが, その量は塩化ビニルのオキシシアン化により得られたフマロニトリルよりぎわめて少なかった。ベンゼンよりベンゾニトリルが得られた ...
Naoya KOMINAMI +3 more
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Synthesis and Evaluation of Thiochroman-4-One Derivatives as Potential Leishmanicidal Agents
Molecules, 2017 The S-containing heterocyclic compounds benzothiopyrans or thiochromones stand out as having promising biological activities due to their structural relationship with chromones (benzopyrans), which are widely known as privileged scaffolds in medicinal ...
Esteban Vargas +4 more
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Beilstein Journal of Organic Chemistry, 2021 The reported flow-batch approach enables the easy preparation of 2H-azirines and their stereoselective transformation into highly functionalized NH-aziridines, starting from vinyl azides and organolithium compounds.
Michael Andresini +2 more
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The Chlorination of Vinyl Compounds in Alcohols [PDF]
Bulletin of the Chemical Society of Japan, 1988 Abstract Upon the chlorination of vinyl compounds in alcohols, the reaction products were composed of 2-alkoxy-1-chloro compound (A), 1-alkoxy-2-chloro compound (B) and vicinal dichloride (C). Various vinyl compounds were chlorinated in alcohols at 40 °C in order to elucidate the effect of their molecular structure on the product ...
Kiyonori Shinoda, Kensei Yasuda
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Журнал органічної та фармацевтичної хімії, 2020 Aim. To study the synthetic potential of cyclization of N-(β-polyfluoroacyl)vinyl derivatives of proline and N-substituted glycines into polyfluoroalkyl pyrroles, which are useful intermediates to fluorinated pyrrolidine alkaloids.
Anton A. Klipkov +3 more
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, 2014 The authors acknowledge the Scottish Funding Council for a SPIRIT Studentship (M.A.) and the EPSRC (EP/K000411/1) for financial support, and D.O’H. acknowledges the European Research Council for an Advanced Grant and the Royal Society for a Wolfson ...
Hähner, Georg +8 more
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