Results 151 to 160 of about 2,799,905 (389)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

A Three-fold (Homiletic) Lesson from Dr. King’s Pastoral and Prophetic Preaching on Violence

open access: yes, 2018
In 1992 when Walter Wink stated in his Engaging the Powers, “Violence is the ethos of our times. It is the spirituality of the modern world,” he was more than right.1 Nowadays, we experience violence everywhere we breathe, walk, and look, even though not
Yang, Sunggu
core  

Physical and Psychological Violence at the Workplace [PDF]

open access: yes, 2013
[Excerpt] Key findings Workplace violence is a social phenomenon of a certain magnitude. Overall, approximately 6% of European workers report having experienced some form of workplace violence, either physical or psychological, in the past 12 months ...
Eurofound
core   +1 more source

Proactive psychosocial follow-up of youth exposed to a terrorist attack: longitudinal study linking interviews and register-based data

open access: yesBJPsych Open
Background Knowledge on efficient approaches to the provision of post-disaster psychosocial care is urgently needed. To prevent unmet healthcare needs, proactive follow-up by municipal contact persons was recommended for survivors of the Utøya youth camp
Lise Eilin Stene   +4 more
doaj   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee   +9 more
wiley   +1 more source

A Colloquy on Violence and Non-Violence: Towards a Complementary Conflict Resolution [PDF]

open access: yes, 2017
In conflict resolution discourse the two challenging and contrasting concepts, violence and non-violence, are often presented as opposites and contradictory. On the basis of this, one is affirmed against the other.
Ibanga, Diana-Abasi
core  

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

Law, Social Movements, and the Political Economy of Domestic Violence [PDF]

open access: yes, 2013
This article uses the occasion of the 2013 Reauthorization of the Violence Against Women Act (VAWA) to review the circumstances by which legal theory and social movement discourse have circumscribed the scope of VAWA and the dominant approach to domestic
Weissman, Deborah M.
core   +2 more sources

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