Results 171 to 180 of about 2,799,905 (389)
Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza+3 more
wiley +1 more source
Re L (Contact: Domestic Violence; Re V (Contact: Domestic Violence; Re M (Contact:Domestic Violence; Re H (Contact: Domestic Violence) [PDF]
This is the post-print version of the ...
Kaganas, F
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The world report on violence and health
E. Krug, J. Mercy, L. Dahlberg, A. Zwi
semanticscholar +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Violence against American Indian and Alaska Native Women and Men [PDF]
Information generated by the National Institute of Justice, Office of Justice Programs, is in the public domain (http://www.nij.gov/publications/pages/reuse-policy.aspx).
Rosay, André B.
core
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Descriptive Analysis of Domestic Violence and Sexual Assault Incidents Closed by the Alaska State Troopers: 2008–2011 — Final Report [PDF]
This report presents a descriptive analysis of sexual assault and domestic violence incidents closed by the Alaska State Troopers for the period January 1, 2008 through December 31, 2011, as part of an effort to systematically document the formal ...
Myrstol, Brad A., Parker, Khristy L.
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Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley +1 more source
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira+14 more
wiley +1 more source
Descriptive Analysis of Assaults in Domestic Violence Incidents Reported to Alaska State Troopers: 2004 [PDF]
This project examined the characteristics of assaults in domestic violence incidents reported to the Alaska State Troopers. Assaults are only one type of criminal offense defined in Alaska statutes as a crime involving domestic violence.
Postle, Greg+6 more
core