Results 31 to 40 of about 8,731,984 (297)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Regulation of domestic violence: a global perspective

BMC Public Health
Background This study examines the global evolution of the laws addressing domestic violence (DV), providing insights on the number and types of laws adopted by countries around the world since early 1980s.
Jane Fisher, Erica Lukas, Astghik Mavisakalyan, Jacqui True   +3 more
doaj   +1 more source

Correction: Modelling collective action to change social norms around domestic violence: social dilemmas and the role of altruism

Humanities & Social Sciences Communications, 2021
A Correction to this paper has been published: https://doi.org/10.1057/s41599-021-00771 ...
Lu Gram, Rolando Granados, Eva M. Krockow, Nayreen Daruwalla, David Osrin   +4 more
doaj   +1 more source

Clinical Neuropsychological Profile and Quality of Life in Women Who Have Suffered Gender-Based Violence

Women's Health Reports, 2023
Background: This research characterizes the clinical and neuropsychological profiles and the quality of life in a group of Ecuadorian women who suffered physical violence, psychological violence, or sexual violence, exploring their relationships with ...
Alexandra Yakeline Meneses Meneses, Sol Fernandez-Gonzalo, Merc? Jodar Vicente   +2 more
doaj   +1 more source

Violence against Pregnant Women in Indonesia

Iranian Journal of Public Health, 2022
Background: Generally, violence against women, especially during pregnancy, can increase the risk of pregnancy and childbirth complications. Besides, multiple trauma may occur because it affects not only the woman but also the fetus. The present study analyzed the factors associated with violence against pregnant women in Indonesia.
Agung Dwi Laksono, -, Ratna Dwi Wulandari, -   +1 more
openaire   +4 more sources

Gender equality and violence against women: what’s the connection? [PDF]

, 2014
A lack of gender equality is consistently cited as an underlying determinant of violence against women. The United Nations General Assembly, in its 1993 Declaration on the Elimination of Violence Against Women, noted that this violence is a manifestation
Liz Wall
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Health and the primary prevention of violence against women [PDF]

, 2014
This position paper focuses on the primary prevention of violence perpetrated by men against women. It develops a position on primary prevention (as distinct from secondary and tertiary interventions).

core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Factors associated with recent intimate partner violence experience amongst currently married women in Afghanistan and health impacts of IPV: a cross sectional study

BMC Public Health, 2018
Background Intimate partner violence (IPV) is exceedingly common in conflict and post-conflict settings. We first seek to describe factors associated with past 12 month IPV amongst currently married women in Afghanistan, focused on the factors typically ...
Andrew Gibbs, Julienne Corboz, Rachel Jewkes   +2 more
doaj   +1 more source