Results 151 to 160 of about 89,092 (251)

DNA‐Induced Entropic Gain Triggers an Allosteric Switch for Biomolecular Condensation of Heat Shock Transcription Factor 1

open access: yesAngewandte Chemie, EarlyView.
Hsf1 undergoes phase separation around target DNA, activating stress‐responsive transcription. DNA binding tunes conformational dynamics of Hsf1DBD, which propagates through large‐scale domain rearrangements involving DBD–IDR interactions to regulate phase separation. This hierarchical framework illustrates how local structural events at the side chain
Soichiro Kawagoe   +2 more
wiley   +2 more sources

Structural Control of Dual Emission in Coumarin Fluorophores for Visualizing Protein Droplet Maturation

open access: yesAngewandte Chemie, EarlyView.
A coumarin‐based dual‐emission fluorophore was designed to visualize the maturation of protein liquid droplets. Upon covalent conjugation to droplet‐forming proteins, ratiometric fluorescence imaging allowed real time monitoring of droplet maturation. This probe is applicable to the analysis of droplet formation and maturation mechanisms, as well as to
Tomoya Yamamoto   +6 more
wiley   +2 more sources

Experts' subjective theories: how did they explain post-pandemic school violence in their public discourse through digital media? [PDF]

open access: yesFront Sociol
Zelaya M   +7 more
europepmc   +1 more source

Experienced and Anticipated Intersectional Violence and Psychological Distress Symptom Severity Among Black Transgender Women in the United States of America. [PDF]

open access: yesHealthcare (Basel)
Sherman ADF   +11 more
europepmc   +1 more source

Characterising resilient and at-risk neighbourhoods with lower-than-expected and higher-than-expected firearm injuries and fatalities in Pittsburgh, Pennsylvania. [PDF]

open access: yesInj Prev
Ortiz-Whittingham L   +10 more
europepmc   +1 more source

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