Results 31 to 40 of about 92,388 (260)

Characterization of a Bacillus thuringiensis strain collection isolated from diverse Costa Rican natural ecosystems

Revista de Biología Tropical, 2006
Costa Rican natural ecosystems are among the most diverse in the world. For this reason, we isolated strains of the entomopathogenic bacteria Bacillus thuringiensis (Bt ) to determine their diversity, distribution and abundance. A total of 146 Bt strains
Glen Arrieta, Ana M Espinoza
doaj  

Compilación de un corpus especializado de joyería para la traducción e interpretación con la herramienta VIP

Estudios de Lingüística
En la actualidad, el comercio internacional de joyería está experimentando un repentino crecimiento lo que ha dado lugar a la celebración de ferias y exhibiciones en diversos países de todo el mundo. Esta situación ha originado una prolífica aparición de
Encarnación Postigo Pinazo, María de la Presentación Aguilera Crespillo   +1 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Study on the second personalized chair ⁃ side education to change the knowledge, attitude, and practice of patients with periodontitis

口腔疾病防治, 2018
Objective To explore the application effect of secondary personalized chairside education on changing the knowledge and behavior of patients with oral periodontal disease.
YE Huiming, ZHU Xiaobin, ZHANG Yangqing, ZHOU Qiaoyi, XU Lin, ZENG Yinghuai   +5 more
doaj   +1 more source

The Role of VIP in Cornea [PDF]

Investigative Opthalmology & Visual Science, 2012
Exogenous vasoactive intestinal peptide (VIP) down-regulates pro-inflammatory but up-regulates anti-inflammatory cytokines, growth factors (GFs) and Toll-like receptors promoting healing in experimental Pseudomonas aeruginosa (P. aeruginosa) keratitis.
Xiaoyu, Jiang, Sharon A, McClellan, Ronald P, Barrett, Yunfan, Zhang, Megan E, Foldenauer, Linda D, Hazlett   +5 more
openaire   +2 more sources

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

社区老年人群预防跌倒干预措施：美国预防服务工作组推荐声明 Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force

Zhongguo cuzhong zazhi, 2018
重要性 跌倒是美国老年人群中首位伤害相关的致残和致死原因。2014年，28.7%社区65岁及以上 老年人经历过跌倒，导致2015年2900万次跌倒（37.5%需要药物治疗或1 d及以上的限制活动），估计 有3.3万人死亡。 目的 更新2012年美国预防服务工作组（US Preventive Services Task Force，USPSTF）针对社区老年人 跌倒预防措施的推荐意见。 证据回顾 USPSTF回顾了针对无骨质疏松及维生素D缺乏的社区65岁及以上老年人群预防跌倒及跌 ...
译者：李金鑫，李宁，高婷，刘丽君，鞠奕，赵性泉
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source