Results 141 to 150 of about 1,959,636 (236)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

High-Throughput Virome Surveillance Reveals Emerging Viral Threats to Cucumber Production in Taiwan. [PDF]

Viruses
Chen TC, Lin CC, Chen PC.
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Yeni geliştirilmiş bir takviye edici ürünün anti-influenza virüs aktivitesinin ın vitro ve ın vivo araştırılması

Bitkisel bazı ürünler sağlığı destekleyici olarak tasarlanmakta ve takviye edici ürünolarak ticarileştirilerek piyasada dolaşıma sürülmektedir. Bununla birlikte, bu ürünlerinçoğunun biyolojik özellikleri, bilimsel kurallar uygulanarak ve standardize bir ...
NESLİHAN AYDEMİR
core  

The Evolving Landscapes of Invisible Invaders: Global Insights on Plant Viruses and Vector Complexes. [PDF]

Viruses
Kumari S, Divekar PA, Karkute SG, Devraj, Singh AN, Kumar R.   +5 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Isparta yöresinde farklı gruplarda SEN virüs sıklığı /

, 2008
Akut ve kronik hepatitli hastaların bir kısmında bilinen hepatit virüsleri tespit edilememekte olup bu hepatitler non A-non E hepatit olarak sınıflandırılmaktadır. Non A-non E hepatit etkenleri konusu üzerine araştırmalar devam etmektedir.
11545 Akçam, Füsun Zeynep, 1966- thesis advisor, Süleyman Demirel Üniversitesi. Tıp Fakültesi. Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı. 10685 issuing body, Demir, Canan. 18667 author   +2 more
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Comprehensive Performance Verification of the Mindray MN2880 System in Detecting Respiratory Virus Nucleic Acids. [PDF]

J Clin Lab Anal
Chen J, Zeng L, Huang H, Chen P.
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

Domuz Gribi İnsandan Hayvana Geçti

, 2009
Kanada’nın Alberta eyaletinde, Meksika’dan tatilden dönen bir domuz çiftliği işçisinden, çiftlikteki domuzlara virüs bulaştığı ...

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