Results 41 to 50 of about 1,959,636 (236)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

El Ülseri: Ecthyma Contagiosum(Orf)

open access: yesSakarya Tıp Dergisi, 2012
Orf hastalığında, lezyonların ağrılı olması, kendiliğinden iyileşmesi, hayvan teması ve ülser öyküsü tanı için önemlidir.
Gökçen Öztürk   +2 more
doaj   +1 more source

Epidemiology and clinical characteristics of Chandipura virus

open access: yesJournal of Zoonotic Diseases
Chandipura virus is an emerging arbovirus that poses significant public health challenges, especially in South Asia. Chandipura virus infection is one of the neglected diseases that is receiving limited attention.
Epidemiology and clinical characteristics of Chandipura virus
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Muğla İlinde Virüs ve Virüs Benzeri Hastalıklardan Arındırılmış Turunçgil Fidanı Üretimi

open access: yes, 2004
İbrahim Yokaş'ın Muğla İlinde Virüs ve Virüs Benzeri Hastalıklardan Arındırılmış Turunçgil Fidanı Üretimi adlı ...
Yokaş, İbrahim
core  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

KRONİK HEPATİTİS B VİRÜS İNFEKSİYONUNDA PATOGENEZ

open access: yes, 2000
Hepatitis B virüs, (HBV) infeksiyonunu izleyerek çeşitli klinik tablolar ortaya ...
ERDENİZMENLİ, Mine
core  

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