Results 51 to 60 of about 2,913,940 (309)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hepatic Encephalopathy in a 76-year-old Female with Reactivation of Chronic Hepatitis B due to Cytomegalovirus Infection: A Case Report [PDF]

Reviews in Clinical Medicine
This case report documents a unique presentation of hepatic encephalopathy induced by the reactivation of chronic hepatitis B due to Cytomegalovirus (CMV) infection in a 76-year-old female patient.
samaneh mortezaei, Mitra Ahadi, seyedmorteza valayi   +2 more
doaj   +1 more source

Measuring Population Transmission Potential for HIV: An Alternative Metric of Transmission Risk in Men who have Sex with Men (MSM) in the US [PDF]

, 2012
Background Various metrics for HIV burden and treatment success [e.g. HIV prevalence, community viral load (CVL), population viral load (PVL), percent of HIV-positive persons with undetectable viral load] have important public health limitations for ...
del Rio, Carlos, Frew, Paula M., Kelley, Colleen F., O\u27Hara, Brandon M., Peterson, John L., Rosenberg, Eli S., Sanchez, Travis, Sullivan, Patrick S.   +7 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Impact on Patient Management of a Novel Host Response Test for Distinguishing Bacterial and Viral Infections: Real World Evidence from the Urgent Care Setting

Biomedicines, 2023
Antibiotic overuse and underuse are prevalent in urgent care settings, driven in part by diagnostic uncertainty. A host-based test for distinguishing bacterial and viral infections (MeMed BV) has been clinically validated previously. Here we examined how
Boaz Kalmovich, Daniella Rahamim-Cohen, Shirley Shapiro Ben David   +2 more
doaj   +1 more source

Viral Conjunctivitis

Viruses, 2023
Viruses account for 80% of all cases of acute conjunctivitis and adenovirus; enterovirus and herpes virus are the common causative agents. In general, viral conjunctivitis spreads easily. Therefore, to control the spread, it is crucial to quickly diagnose illnesses, strictly implement hand washing laws, and sanitize surfaces. Swelling of the lid margin
Tetsuaya Muto, Shinichiro Imaizumi, Koju Kamoi   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Predictors of Mortality in Patients With Biopsy‐Proven Viral Myocarditis: 10‐Year Outcome Data

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background There is scarce data about the long‐term mortality as well as the prognostic value of cardiovascular magnetic resonance and late gadolinium enhancement (LGE) in patients with biopsy‐proven viral myocarditis.
Simon Greulich, Andreas Seitz, Karin A. L. Müller, Stefan Grün, Peter Ong, Nawid Ebadi, Klaus Peter Kreisselmeier, Peter Seizer, Raffi Bekeredjian, Carolin Zwadlo, Christoph Gräni, Karin Klingel, Meinrad Gawaz, Udo Sechtem, Heiko Mahrholdt   +14 more
doaj   +1 more source

Pathology and viral metagenomics, a recent history [PDF]

, 2013
Human, animal and plant viral pathologies have greatly benefited from recent metagenomics development. Viral metagenomics is a culture-independent approach used to investigate the complete viral genetic populations of a sample.
Albina, Emmanuel, Bernardo, Pauline, Eloit, Marc, Fernandez, Emmanuel, Filloux, Denis, Roumagnac, Philippe   +5 more
core  

Sequence Instability in the Proviral Long Terminal Repeat and gag Regions from Peripheral Blood and Tissue-Derived Leukocytes of FIV-Infected Cats during the Late Asymptomatic Phase. [PDF]

, 2016
Feline immunodeficiency virus (FIV) infection results in viral persistence, a prolonged asymptomatic phase, and progressive immunopathology. During the asymptomatic phase, a cohort of experimentally FIV-infected cats exhibits features of viral latency in
Eckstrand, Christina D, Hillman, Chadwick, Murphy, Brian G   +2 more
core   +3 more sources