Results 1 to 10 of about 965,478 (165)

Whole gene analysis of a genotype G29P[6] human rotavirus strain identified in Central African Republic

BMC Research Notes, 2021
Objective Rotavirus A (RVA) remains the main causative agent of gastroenteritis in young children and the young of many mammalian and avian species. In this study we describe a RVA strain detected from a 6-month-old child from Central African Republic ...
Virginie Banga-Mingo, Mathew D. Esona, Naga S. Betrapally, Rashi Gautam, Jose Jaimes, Eric Katz, Diane Waku-Kouomou, Michael D. Bowen, Ionela Gouandjika-Vasilache   +8 more
doaj   +1 more source

Enhanced dengue vaccine virus replication and neutralizing antibody responses in immune primed rhesus macaques

npj Vaccines, 2021
Antibody-dependent enhancement (ADE) is suspected to influence dengue virus (DENV) infection, but the role ADE plays in vaccination strategies incorporating live attenuated virus components is less clear.
Michael K. McCracken, Caitlin H. Kuklis, Chandrika B. Kannadka, David A. Barvir, Mark A. Sanborn, Adam T. Waickman, Hayden C. Siegfried, Kaitlin A. Victor, Kristin L. Hatch, Rafael De La Barrera, Shannon D. Walls, Wiriya Rutvisuttinunt, Jeffrey R. Currier, Heather Friberg, Richard G. Jarman, Gregory D. Gromowski   +15 more
doaj   +1 more source

Genomic surveillance of SARS-CoV-2 in US military compounds in Afghanistan reveals multiple introductions and outbreaks of Alpha and Delta variants

BMC Genomics, 2022
Background With the emergence and spread of SARS-CoV-2 variants, genomic epidemiology and surveillance have proven invaluable tools for variant tracking.
Irina Maljkovic Berry, Jun Hang, Christian Fung, Yu Yang, Marcus Chibucos, Adam Pollio, Jay Gandhi, Tao Li, Matthew A. Conte, Grace M. Lidl, Jay A. Johannigman, Heather Friberg   +11 more
doaj   +1 more source

Characterization of B-cell and T-cell responses to a tetravalent dengue purified inactivated vaccine in healthy adults

npj Vaccines, 2022
The increasing global impact of dengue underscores the need for a dengue virus (DENV) vaccine. We assessed B-cell and T-cell responses following vaccination with four formulations of a tetravalent dengue purified inactivated vaccine (DPIV) in dengue ...
Heather Friberg, Morgan Gargulak, Amanda Kong, Leyi Lin, Luis J. Martinez, Alexander C. Schmidt, Robert M. Paris, Richard G. Jarman, Clemente Diaz, Stephen J. Thomas, Philippe Moris, Jeffrey R. Currier   +11 more
doaj   +1 more source

A comparative recombination analysis of human coronaviruses and implications for the SARS-CoV-2 pandemic

Scientific Reports, 2021
The SARS-CoV-2 pandemic prompts evaluation of recombination in human coronavirus (hCoV) evolution. We undertook recombination analyses of 158,118 public seasonal hCoV, SARS-CoV-1, SARS-CoV-2 and MERS-CoV genome sequences using the RDP4 software. We found
Simon Pollett, Matthew A. Conte, Mark Sanborn, Richard G. Jarman, Grace M. Lidl, Kayvon Modjarrad, Irina Maljkovic Berry   +6 more
doaj   +1 more source

Emerging viral diseases [PDF]

Proceedings of the National Academy of Sciences, 2000
We live in an era of rapidly changing global landscapes and local environments. Viruses with RNA as their genetic material can quickly adapt to and exploit these varying conditions because of the high error rates of the virus enzymes (polymerases) that replicate their genomes.
S T, Nichol, J, Arikawa, Y, Kawaoka
openaire   +2 more sources

Comprehensive virome analysis of the viral spectrum in paediatric patients diagnosed with Mycoplasma pneumoniae pneumonia

Virology Journal, 2022
Background Among hospitalized children suffering from community-acquired pneumonia, Mycoplasma pneumoniae (MP) is one of the most common pathogens. MP often exists as a co-infection with bacteria or viruses, which can exacerbate the clinical symptoms. We
Qiong Guo, Lili Li, Chao Wang, Yiman Huang, Fenlian Ma, Shanshan Cong, Jingjing Tan, Lihong Yao, Aijun Chen, Lishu Zheng   +9 more
doaj   +1 more source

Epidemiology and genotypic diversity of human metapneumovirus in paediatric patients with acute respiratory infection in Beijing, China

Virology Journal, 2021
Background Acute respiratory tract infections (ARTIs) causes high amounts of morbidity and mortality worldwide every year. Human metapneumovirus (HMPV) is a major pathogen of ARTIs in children.
Chao Wang, Tianli Wei, Fenlian Ma, Hao Wang, Jianqiang Guo, Aijun Chen, Yiman Huang, Zhiping Xie, Lishu Zheng   +8 more
doaj   +1 more source

Human adenoviruses in paediatric patients with respiratory tract infections in Beijing, China

Virology Journal, 2021
Background Human adenoviruse (HAdV) is a major pathogen of paediatric respiratory tract infections (RTIs). Mutation or recombination of HAdV genes may cause changes in its pathogenicity and transmission.
Yiman Huang, Chao Wang, Fenlian Ma, Qiong Guo, Lihong Yao, Aijun Chen, Xiaoyi Luo, Lishu Zheng   +7 more
doaj   +1 more source

Characterizing infection of B cells with wild-type and vaccine strains of measles virus

iScience, 2023
Summary: Acute infection with measles virus (MeV) causes transient immunosuppression often leading to secondary infections. MeV infection of B lymphocytes results in changes in the antibody repertoire and memory B cell populations for which the mechanism
Logan Melot, Bettina Bankamp, Paul A. Rota, Melissa M. Coughlin   +3 more
doaj   +1 more source