Results 121 to 130 of about 40,559 (249)
iMetaMed, EarlyView.Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo +4 more
wiley +1 more source
Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture
iMetaOmics, EarlyView.Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif +4 more
wiley +1 more source
iMetaOmics, EarlyView.The gut–mammary axis integrates intestinal health with mammary function through neural, endocrine, and immune pathways. Nutritional interventions (probiotics, prebiotics, metabolites) improve gut microecology, generating microbial signals that travel via the axis to the mammary gland. There, they relieve inflammation, enhance milk quality and lactation,
Aolong Zhou +29 more
wiley +1 more source
Membrane vesicles in natural environments: a major challenge in viral ecology. [PDF]
ISME J, 2015 Soler N +3 more
europepmc +1 more source
Bile acid metabolism and signaling in human and animal health: A One Health perspective
iMetaOmics, EarlyView.Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li +7 more
wiley +1 more source
iVirus: facilitating new insights in viral ecology with software and community data sets imbedded in a cyberinfrastructure. [PDF]
ISME J, 2017 Bolduc B +4 more
europepmc +1 more source
Viruses in the sediments around the trenches harbor diverse survival mechanisms
iMetaOmics, EarlyView.Deep‐sea trenches are the deepest and most isolated environments in the global ocean but the diversity and adaptation of the viral communities remain poorly characterized. In this study, 5563 viral operational taxonomic units (vOTUs) were identified from sediments of the Yap Trench and Western Caroline Basin.
Yue Su +12 more
wiley +1 more source
Using signature genes as tools to assess environmental viral ecology and diversity. [PDF]
Appl Environ Microbiol, 2014 Adriaenssens EM, Cowan DA.
europepmc +1 more source
Microbial and Viral Ecology Analysis for Metagenomic Data
The explosion in known microbial diversity in the last two decades has made it abundantly clear that microbes in the environment do not exist in isolation; they are members of communities. Accordingly, omics approaches such as metagenomics have revealed that interactions between diverse groups of community members such as archaea, bacteria, and viruses
Kosmopoulos, James C. +1 more
openaire +2 more sources
Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention
iMetaOmics, EarlyView.The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie +12 more
wiley +1 more source