Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection [PDF]
Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR) signaling regulates the responses of endothelial cells of the blood-brain barrier (BBB) during neurotropic viral infection.
Ali+23 more
core +3 more sources
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T+11 more
core +1 more source
Zika virus infection in the returning traveller: what every neurologist should know [PDF]
Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers ...
Brito Ferreira, Maria Lucia+6 more
core +5 more sources
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
Buckley, A.+5 more
core +3 more sources
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi+3 more
core +2 more sources
Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review. [PDF]
BackgroundCanine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder.
Cooper, JJ+7 more
core +1 more source
West Nile virus transmission. results from the integrated surveillance system in Italy, 2008 to 2015 [PDF]
IIn Italy a national Plan for the surveillance of imported and autochthonous human vector-borne diseases (chikungunya, dengue, Zika virus disease and West Nile virus (WNV) disease) that integrates human and veterinary (animals and vectors) surveillance ...
Angelini, P.+53 more
core +1 more source
Post vaccinal temporary sensorineural hearing loss [PDF]
In our systematic research we identified four studies concerning the onset of neurological adverse events following vaccination and two excluding this association.
De Cesare, Donato Pompeo+8 more
core +1 more source
Human infections associated with wild birds. [PDF]
IntroductionWild birds and especially migratory species can become long-distance vectors for a wide range of microorganisms. The objective of the current paper is to summarize available literature on pathogens causing human disease that have been ...
Bauchinger, Ulf+4 more
core +1 more source
Viral Meningitis and Encephalitis
Abstract Viral meningitis and encephalitis occur at all stages of life. They may represent disease at its primary site of replication (e.g. rabies) or be part of an infection syndrome (e.g. HIV). A large proportion of cases go unconfirmed by laboratory diagnosis despite use of all available laboratory techniques.
openaire +2 more sources