Results 81 to 90 of about 944,610 (376)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

PREVALENCE OF HEPATITIS E MARKERS IN CHILDREN

Журнал микробиологии, эпидемиологии и иммунобиологии, 2015
Aim. Frequency of detection determination for past and current hepatitis E virus (HEV) infection markers in children with immune suppression, as well as children with normal immune status. Materials and methods.
I. A Potemkin, M. A Lopatukhina, O. A Gadzhieva, E. L Prokhorova, A. Diyarrassuba, O. V Isaeva, T. V Kozhanova, O. E Ivanova, O. V Silenova, N. Kh Setdikova, K. K Kyuregyan, M. I Mikhailov   +11 more
doaj  

Serological evidence for Japanese encephalitis and West Nile virus infections in domestic birds in Cambodia [PDF]

, 2020
Mosquito-borne flaviviruses with an enzootic transmission cycle like Japanese encephalitis virus (JEV) and West Nile virus (WNV) are a major public health concern.
Auerswald, Heidi, Cappelle, Julien, Chevalier, Véronique, Duong, Veasna, Dussart, Philippe, In, Saraden, Ladreyt, Héléna, Mao, Sokthearom, Ruget, Anne-Sophie, Sorn, San, Tum, Sothyra   +10 more
core   +3 more sources

Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain

Advanced Materials, EarlyView.
A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng, Xiong Wang, Cien Chen, Di Wang, Changshun Hou, Yiran Wang, Huan Hu, Peiran Chen, LeiYing Qin, Qianya Wan, Xi Yao, Ming‐Liang He   +11 more
wiley   +1 more source

Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review. [PDF]

, 2014
BackgroundCanine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder.
Cooper, JJ, Levine, JM, Porter, BF, Schatzberg, SJ, Siso, S, Summers, BA, Vernau, KM, Young, BD   +7 more
core   +1 more source

EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets

Advanced Science, EarlyView.
Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang, Fujun Hou, Xunuo Jin, Yuhang Xiang, Dongli Pan   +4 more
wiley   +1 more source

Role of MR Imaging in Viral Encephalitis-A Clue Towards Aaetiological Agent

International Journal of Anatomy Radiology and Surgery, 2018
Introduction: MRI plays a significant role in diagnosing viral encephalitis. It aids the diagnosis of causative agent, conditions mimicking the disease, identification of complications and hence prognostication of the patient.
Kamini Gupta, Avik Banerjee, Rama Gupta, Monika Singla   +3 more
doaj   +1 more source

West Nile virus transmission. results from the integrated surveillance system in Italy, 2008 to 2015 [PDF]

, 2016
IIn Italy a national Plan for the surveillance of imported and autochthonous human vector-borne diseases (chikungunya, dengue, Zika virus disease and West Nile virus (WNV) disease) that integrates human and veterinary (animals and vectors) surveillance ...
Angelini, P., Baldanti, Fausto, Bedeschi, Emanuela, Bella, A., Bellini, R., Benedetti, Eleonora, Boccolini, Daniela, Busani, Luca, Cagarelli, R., Calistri, P., Cenci, Corrado, Chiari, M., Costa, Nanni, Declich, Silvia, di Luca, Marco, Dottori, Michele, Faccin, Francesca, Farioli, Marco, Fiorentini, Cristiano, Fortuna, Claudia, Gismondo, Mariarita, Gramegna, Maria, Gualanduzzi, Claudio, Landini, Maria Paola, Lavazza, A., Lelli, Davide, Liumbruno, Giancarlo Maria, Lombardini, Annalisa, Lombardini, L., Maraglino, Francesco, Mattivi, Andrea, Monaco, F., Napoli, Christian, Natalini, Silvano, Palú, G., Parodi, Patrizia, Pezzotti, Patrizio, Piatti, A., Prosperi, Alice, Pupella, S., Remoli, Maria Elena, Rezza, Gianni, Rizzo, Caterina, Romi, Roberto, Rossi, Davide, Rovida, Francesca, Russo, F., Severini, Francesco, Squintani, Gabriele, Tamba, M., Toma, Luciano, Venturi, G., Zanchetta, Nadia, Zanella, Francesca   +53 more
core   +1 more source

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

Animal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao, Ming Zhong, Wenjiang Zheng, Zhendong Guo, Ye Zhou, Qiuhong Li, Lijuan Qiu, Liangwen Yu, Haishan Long, Geng Li   +9 more
wiley   +1 more source

The Advent Of Cytomegalovirus Infection In HIV Infected Patients: A review [PDF]

, 2004
Cytomegalovirus is considered as one among the long list of latent infections in humans that although normally controlled by the cellular immune response, gets activated after HIV infection takes its role on infecting the T4 lymphocytes. Clinical disease
Kirubakaran Isaac, Dr Sundar
core   +1 more source