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Viral Membrane Fusion and the Transmembrane Domain
Initiation of host cell infection by an enveloped virus requires a viral-to-host cell membrane fusion event. This event is mediated by at least one viral transmembrane glycoprotein, termed the fusion protein, which is a key therapeutic target.
Rebecca Ellis Dutch
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Fusion peptides and the mechanism of viral fusion
Segments of viral fusion proteins play an important role in viral fusion. They are defined by a number of criteria, including the sensitivity of this region of the viral fusion protein to loss of function as a consequence of mutation.
Richard M Epand
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Trimeric coiled-coils as viral fusion protein mimics
2008α-Helical coiled-coils, a protein structural motif formed by supercoiling of two or more component polypeptide strands, are ubiquitous mediators of biological structure and function. Their characteristic primary heptad repeat, denoted abcdefg, makes these complexes attractive scaffolds for studying self-assembly and molecular recognition.
Travisano, Philip, Kennan, Alan J.
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Structural comparison of three viral “fusion” proteins
Biochemical Society Transactions, 1991B H, Nicholson, M, Naase
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Viral and Cellular Membrane Fusion Proteins
Annual Review of Physiology, 1990openaire +2 more sources
Probing the Function of Viral Fusion Proteins with Synthetic Peptides
1987Synthetic peptides offer several unique approaches to studying molecular and cellular interactions. Not only do these peptides provide A. large quantity of material for experimental analysis, but they also offer A. degree of homogeneity that is difficult to obtain through routine biochemical purification.
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Structures and Mechanisms of Viral Membrane Fusion Proteins: Multiple Variations on a Common Theme
Critical Reviews in Biochemistry and Molecular Biology, 2008Judith M White +2 more
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