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Viral Hemorrhagic Fever Diagnostics. [PDF]

Clin Infect Dis, 2016
There are 4 families of viruses that cause viral hemorrhagic fever (VHF), including Filoviridae. Ebola virus is one virus within the family Filoviridae and the cause of the current outbreak of VHF in West Africa. VHF-endemic areas are found throughout the world, yet traditional diagnosis of VHF has been performed in large reference laboratories ...
Racsa LD, Kraft CS, Olinger GG, Hensley LE.   +3 more
europepmc   +6 more sources

Clinical Characterization of Host Response to Simian Hemorrhagic Fever Virus Infection in Permissive and Refractory Hosts: A Model for Determining Mechanisms of VHF Pathogenesis [PDF]

Viruses, 2019
Simian hemorrhagic fever virus (SHFV) causes a fulminant and typically lethal viral hemorrhagic fever (VHF) in macaques (Cercopithecinae: Macaca spp.) but causes subclinical infections in patas monkeys (Cercopithecinae: Erythrocebus patas).
Joseph P. Cornish, Ian N. Moore, Donna L. Perry, Abigail Lara, Mahnaz Minai, Dominique Promeneur, Katie R. Hagen, Kimmo Virtaneva, Monica Paneru, Connor R. Buechler, David H. O’Connor, Adam L. Bailey, Kurt Cooper, Steven Mazur, John G. Bernbaum, James Pettitt, Peter B. Jahrling, Jens H. Kuhn, Reed F. Johnson   +18 more
doaj   +3 more sources

Viral Hemorrhagic Fever Preparedness [PDF]

Infection PreventionNew Perspectives and Controversies, 2017
The 2014–2016 outbreak of Ebola virus disease (EVD) in West Africa marked the 25th such occurrence but was noteworthy in its massive scope, causing more human morbidity and mortality than the previous 24 recorded outbreaks combined. As of April 2016, there were 28,652 cases resulting in at least 11,325 deaths, nearly all in the three nations of Guinea,
Hewlett A, Vasa A, Cieslak T, Lowe J, Schwedhelm S.   +4 more
europepmc   +2 more sources

Does electrocardiography at admission predict outcome in Crimean-Congo hemorrhagic fever [PDF]

Journal of Vector Borne Diseases, 2011
Background & objectives: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever withconsiderable mortality. Despite increasing knowledge about hemorrhagic fever viruses, the pathogenesis ofCrimean-Congo hemorrhagic fever and causes of death ...
Mehmet Birhan Yilmaz , Aynur Engin , Gokhan Bektasoglu , Ali Zorlu , Meltem Refiker EGE , Mehmet Bakir & Ilyas Dokmetas
doaj   +2 more sources

Molecular evolution and genetic diversity analysis of SFTS virus based on next-generation sequencing

Biosafety and Health, 2021
SFTS virus (SFTSV) is a novel bunyavirus, which was discovered as the etiological agent of severe fever with thrombocytopenia syndrome (SFTS) in China in 2009, and was now prevalent in at least 25 provinces in China.
Aqian Li, Lin Liu, Wei Wu, Yang Liu, Xiaoxia Huang, Chuan Li, Di Liu, Jiandong Li, Shiwen Wang, Dexin Li, Mifang Liang   +10 more
doaj   +1 more source

Immunogenicity and protective efficacy of an inactivated SFTS vaccine candidate in mice

Biosafety and Health, 2022
Severe fever with thrombocytopenia syndrome (SFTS), caused by a novel identified bunyavirus SFTS virus (SFTSV), was an emerging viral infectious disease that was firstly reported in China.
Aqian Li, Xinxian Dai, Lei Chen, Lin Liu, Chuan Li, Yang Liu, Wei Wu, Xiaoxia Huang, Jiandong Li, Shiwen Wang, Mifang Liang, Xiuling Li, Dexin Li   +12 more
doaj   +1 more source

Evaluation of an Assay of Zika Virus Detection Without RNA Extraction

Xiehe Yixue Zazhi, 2022
Objective  To evaluate a Zika virus(ZIKV) test based on real-time reverse-transcriptase-polymerase chain reaction (rRT-PCR) that can be performed without RNA isolation.  Methods  The detection method is based on rRT-PCR technology, and a virus-enrichment
LI Aqian, KONG Lingjun, LIU Yang, YI Jie, LI Chuan, LIANG Mifang, DOU Yaling   +6 more
doaj   +1 more source

First molecular analysis of rabies virus in Qatar and clinical cases imported into Qatar, a case report

International Journal of Infectious Diseases, 2020
Identifying the origin of the rabies virus (RABV) infection may have significant implications for control measures. Here, we identified the source of a RABV infection of two Nepalese migrants in Qatar by comparing their RABV genomes with RABV genomes ...
Bas B. Oude Munnink, Elmoubashar Abu Baker Abd Farag, Corine GeurtsvanKessel, Claudia Schapendonk, Anne van der Linden, Robert Kohl, Georgina Arron, Hisham Ziglam, Wael Goravey Mhjoop Goravey, Peter V. Coyle, Imad Ibrahim, Khaled A. Mohran, Muneera Mohammed Saleh Alrajhi, Md Mazharul Islam, Randa Abdeen, A. Aziz Mahmoud A.H. Al-Zeyara, Nidal Mahmoud Younis, Hamad Eid Al-Romaihi, Mohammad Hamad J. Al Thani, Richard Molenkamp, Reina S. Sikkema, Marion Koopmans   +21 more
doaj   +1 more source

Atypical presentation of mpox in Irrua environs: a case report

Journal of Medical Case Reports, 2023
Background Mpox, previously known as monkeypox, -is an orthopoxvirus infection of the skin and previously a public health emergency of international concern. It reemerged in Nigeria over 5 years ago and has since spread to other parts of the world.
S. O. Oiwoh, E. A. Tobin, D. A. Asogun, C. O. Erameh, K. O. Iraoyah, J. Okoeguale, R. A. Eifediyi, S. O. Samuel, T. A. T. Salami, S. A. Okogbenin   +9 more
doaj   +1 more source

Viral hemorrhagic fevers. [PDF]

Advances in pediatric infectious diseases, 1997
A 15-year-old European boy, who had been in Kenya for 1 month, was admitted to the hospital with a 3-day history of headache, malaise, anorexia, fever, and vomiting. Throughout the course of the illness, he developed copious bloody diarrhea, hypotension, leukocytosis, thrombocytopenia, and prolonged prothrombin and partial thromboplastin times ...
M D, Lacy, R A, Smego
  +5 more sources