Results 31 to 40 of about 299,917 (158)

Universal Single-Dose Vaccination against Hepatitis A in Children in a Region of High Endemicity

Vaccines, 2020
Since August 2012, universal single-dose vaccination in children aged at least three years has been implemented in the Republic of Tuva, which was previously the region most affected by hepatitis A in Russia.
Mikhail I. Mikhailov, Maria A. Lopatukhina, Fedor A. Asadi Mobarhan, Lyudmila Yu. Ilchenko, Tatyana V. Kozhanova, Olga V. Isaeva, Anastasiya A. Karlsen, Ilya A. Potemkin, Vera S. Kichatova, Anna A. Saryglar, Natalia D. Oorzhak, Karen K. Kyuregyan   +11 more
doaj   +1 more source

The Interleukin-6 gene variants may protect against SARS-CoV-2 infection and the severity of COVID-19: a case-control study in a Moroccan population

BMC Medical Genomics
The symptoms of SARS-CoV-2 infection vary widely, ranging from asymptomatic cases to severe forms marked by acute respiratory distress syndrome, multi-organ damage, and fatalities.
Rachid Noureddine, Hanâ Baba, Safaa Aqillouch, Karima Abounouh, Oumaima Laazaazia, Mohcine Elmessaoudi-Idrissi, Fatima Zohra Bahmani, Ikram Allah Tanouti, Ahd Ouladlahsen, M’hammed Sarih, Hind Dehbi, Sayeh Ezzikouri   +11 more
doaj   +1 more source

Low frequency of NS5A relevant resistance-associated substitutions to Elbasvir among hepatitis C virus genotype 1a in Spain: a cross-sectional study

Scientific Reports, 2017
Relevant resistance-associated substitutions (RASs) to elbasvir, the new HCV NS5A inhibitor, may limit its efficacy and lead to virological failure in HCV-GT1a-infected patients.
Claudia Palladino, Marta Sánchez-Carrillo, Irene Mate-Cano, Sonia Vázquez-Morón, Ma Ángeles Jimenez-Sousa, Mónica Gutiérrez-Rivas, Salvador Resino, Verónica Briz   +7 more
doaj   +1 more source

Hepatitis A Strain Linked to the European Outbreaks During Gay Events between 2016 and 2017, Identified in a Brazilian Homosexual Couple in 2017

Viruses, 2019
Hepatitis A virus (HAV) outbreaks among men who have sex with men (MSM) have been reported worldwide and associated primarily with sexual transmission through oral-anal sex. Here, we provide the molecular and evolutionary description of a European strain,
Vinicius M. Mello, Barbara V. Lago, Paulo S. F. Sousa, Francisco C. A. Mello, Caroline B. Souza, Laura C. M. Pinto, Cleber F. Ginuino, Carlos A. S. Fernandes, Shirlei F. Aguiar, Lívia M. Villar, Elisabeth Lampe, Juliana G. Melgaço, Lia L. Lewis-Ximenez   +12 more
doaj   +1 more source

Natural antibody IgG levels are associated with HBeAg-positivity and seroconversion in chronic hepatitis B patients treated with entecavir

Scientific Reports, 2022
B1 cell-derived natural antibodies are non-specific polyreactive antibodies and can activate the complement pathway leading to lysis of enveloped virus particles before activation of the adaptive immune response.
Youkyung H. Choi, Hyun Woong Lee, Michael A. Purdy   +2 more
doaj   +1 more source

Diversity of human astroviruses in Germany 2018 and 2019

Virology Journal, 2022
Aim of this study was to investigate the molecular diversity of human astroviruses (HAstV) in Germany. A follow-up study was performed with human stool samples collected in 2018–2019, which were genotyped retrospectively.
Sandra Niendorf, Andreas Mas Marques, Claus-Thomas Bock, Sonja Jacobsen   +3 more
doaj   +1 more source

Transmissibility of intra-host hepatitis C virus variants

BMC Genomics, 2017
Background Intra-host hepatitis C virus (HCV) populations are genetically heterogeneous and organized in subpopulations. With the exception of blood transfusions, transmission of HCV occurs via a small number of genetic variants, the effect of which is ...
David S. Campo, June Zhang, Sumathi Ramachandran, Yury Khudyakov   +3 more
doaj   +1 more source

Neuroimmune modulation in liver pathophysiology

Journal of Neuroinflammation
The liver, the largest organ in the human body, plays a multifaceted role in digestion, coagulation, synthesis, metabolism, detoxification, and immune defense.
Ju Zou, Jie Li, Xiaoxu Wang, Daolin Tang, Ruochan Chen   +4 more
doaj   +1 more source

Prevalence of hepatitis B and C virus infections among military personnel

Brazilian Journal of Infectious Diseases, 2015
Background: Data regarding Hepatitis B and C viruses (HBV and HCV) prevalence among military personnel in Brazil are lacking, but the work-related risk of exposure can be high. The objective of this study was to estimate the seroprevalence of HBV and HCV
Livia M. Villar, Kycia Maria R. do Ó, Leticia P. Scalioni, Helena M. Cruz, Moyra M. Portilho, Ana Carolina F. Mendonça, Juliana C. Miguel, Andreza S. Figueiredo, Adilson J. de Almeida, Elisabeth Lampe   +9 more
doaj   +1 more source

The Immunological and Epidemiological Effectiveness of Pediatric Single-Dose Vaccination against Hepatitis A 9 to 11 Years after Its Implementation in the Tyva Republic, the Russian Federation

Vaccines
Since 2012, universal single-dose HAV vaccination in children aged 3 years and older has been implemented in the Tyva Republic, a region of the Russian Federation.
Maria A. Lopatukhina, Karen K. Kyuregyan, Anastasia A. Karlsen, Fedor A. Asadi Mobarkhan, Ilya A. Potemkin, Vera S. Kichatova, Olga V. Isaeva, Lyudmila Yu. Ilchenko, Anna A. Saryglar, Mikhail I. Mikhailov   +9 more
doaj   +1 more source