Results 91 to 100 of about 623,045 (205)

Pellino Proteins in Viral Immunity and Pathogenesis. [PDF]

Viruses, 2023
Jensen LE.
europepmc   +1 more source

Persistence of KIRneg NK cells after haploidentical hematopoietic stem cell transplantation protects from human cytomegalovirus infection/reactivation

Frontiers in Immunology
Haploidentical hematopoietic stem cell transplantation (h-HSCT) is a therapeutic option to cure patients affected by hematologic malignancies. The kinetics and the quality of immune-reconstitution (IR) impact the clinical outcome of h-HSCT and limit the ...
Clara Di Vito, Nicolò Coianiz, Michela Calvi, Michela Calvi, Sara Terzoli, Sara Terzoli, Elisa Zaghi, Simone Puccio, Alessandro Frigo, Alessandro Frigo, Jacopo Mariotti, Chiara De Philippis, Daniele Mannina, Barbara Sarina, Rossana Mineri, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Luca Castagna, Stefania Bramanti, Armando Santoro, Domenico Mavilio, Domenico Mavilio   +21 more
doaj   +1 more source

Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection

Cell Reports, 2017
NK cells can reduce anti-viral T cell immunity during chronic viral infections, including infection with the lymphocytic choriomeningitis virus (LCMV).
Haifeng C. Xu, Jun Huang, Aleksandra A. Pandyra, Elisabeth Lang, Yuan Zhuang, Christine Thöns, Jörg Timm, Dieter Häussinger, Marco Colonna, Harvey Cantor, Karl S. Lang, Philipp A. Lang   +11 more
doaj   +1 more source

Host factors and early treatments to restrict paediatric HIV infection and early disease progression [PDF]

, 2015
open6noA body of evidence indicates that a threshold level of the virus is required to establish systemic and persistent HIV infection in the host and that this level depends on virus-host interactions.
De Rossi, Anita, Freguja, Riccardo, Gianesin, Ketty, Giaquinto, Carlo, Petrara, Raffaella, Zanchetta, Marisa   +5 more
core   +1 more source

mGem: Immune recognition and clearance of bacteriophages—implications for phage therapy

mBio
Bacteriophages (phages) hold significant promise as targeted antibacterial therapies in the era of rising multidrug-resistant infections. Despite their therapeutic potential, the clinical application of phages for human infections has been significantly ...
H. T. Le, G. Ahlenstiel, C. Venturini, S. A. Read   +3 more
doaj   +1 more source

Recurrent SARS-CoV-2 mutations at Spike D796 evade antibodies from pre-Omicron convalescent and vaccinated subjects

Microbiology Spectrum
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages of the Omicron variant rapidly became dominant in early 2022 and frequently cause human infections despite vaccination or prior infection with other variants.
Evan A. Elko, Heather L. Mead, Georgia A. Nelson, John A. Zaia, Jason T. Ladner, John A. Altin   +5 more
doaj   +1 more source

Innate Immunity in Viral Encephalitis

, 2008
Innate immune responses to pathogens are evolutionarily ancient and are found in the most primitive organisms. These are highly conserved and are not pathogen-specific, but are in response to classes of molecular structures. Infections can be perceived both extracellularly and intracellularly by Pathogen Associated Molecular Patterns (PAMPs) and their ...
openaire   +1 more source

Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity. [PDF]

Cell Rep, 2022
Strine MS, Alfajaro MM, Graziano VR, Graziano VR, Song J, Hsieh LL, Hill R, Guo J, VanDussen KL, Orchard RC, Baldridge MT, Lee S, Wilen CB.   +12 more
europepmc   +1 more source

SARS-CoV-2 mRNA vaccines decouple anti-viral immunity from humoral autoimmunity. [PDF]

Nat Commun, 2023
Jaycox JR, Lucas C, Yildirim I, Dai Y, Wang EY, Monteiro V, Lord S, Carlin J, Kita M, Buckner JH, Ma S, Campbell M, Ko A, Omer S, Lucas CL, Speake C, Iwasaki A, Ring AM.   +17 more
europepmc   +1 more source

Understanding T cell aging to improve anti-viral immunity. [PDF]

Curr Opin Virol, 2021
Zhang H, Weyand CM, Goronzy JJ, Gustafson CE.   +3 more
europepmc   +1 more source