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ZFP36 RNA-binding proteins restrain T cell activation and anti-viral immunity. [PDF]
Elife, 2018 Moore MJ +9 more
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Inhibition of papain-like protease PLpro blocks SARS-CoV-2 spread and promotes anti-viral immunity
, 2020 Shin D +19 more
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Mitochondrial anti-viral immunity
The International Journal of Biochemistry & Cell Biology, 2012In the cytosol, the sensing of RNA viruses by the RIG-I-like receptors (RLRs) triggers a complex signaling cascade where the mitochondrial antiviral signaling protein (MAVS) plays a crucial role in orchestrating the innate host response through the induction of antiviral and inflammatory responses.
Naima, Zemirli, Damien, Arnoult
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Immune Checkpoints in Viral Latency
Annual Review of Microbiology, 2001▪ Abstract The dynamics of the relationship between the immune system and latent viruses are highly complex. Latent viruses not only avoid elimination by the host's primary immune response, they also remain with the host for life in the presence of strong acquired immunity, often exhibiting periodic reactivation and recurrence from the latent state ...
S, Redpath +3 more
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Maternal immunization against viral disease
Vaccine, 1998The protective effect of maternal antibody against many viral diseases has been recognized. The use of maternal immunization has been considered as a means to augment this protection in the young infant against disease. Advantages of maternal immunization include the fact that young infants are most susceptible to infections but least responsive to ...
J, Englund, W P, Glezen, P A, Piedra
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2014
This chapter focuses on the study of viral immune evasion. Most viruses spread from one host to the next via secreted bodily fluids; to gain access to their target cells for replication they need to cross epithelial barriers, which can be considered the first line of host defense.
Lila Farrington +2 more
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This chapter focuses on the study of viral immune evasion. Most viruses spread from one host to the next via secreted bodily fluids; to gain access to their target cells for replication they need to cross epithelial barriers, which can be considered the first line of host defense.
Lila Farrington +2 more
openaire +2 more sources
Measuring immunity in viral hepatitis
Journal of Gastroenterology, 2004chronic HBV or HCV infection, either reduce the viral load or enhance immunity to prevent the subsequent development of liver cirrhosis or hepatocellular carcinoma (HCC).1,2 In addition to providing direct inhibition of viral replication, these agents modulate antiviral immune responses, which greatly contributes to the successful therapeutic response.
Tatsuya, Kanto, Norio, Hayashi
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IMMUNIZATION IN VIRAL HEPATITIS
Journal of the American Medical Association, 1960It is paradoxical that zinc-precipitated gamma globulin administered in small doses apparently could protect the recipient against epidemic hepatitis while the same material may produce serum hepatitis. Cold-ethanolfractionated gamma globulin does not produce serum hepatitis but protects almost all exposed susceptible persons against the more severe ...
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Langerhans cells and viral immunity
European Journal of Immunology, 2008AbstractLangerhans cells (LC) are a unique dendritic cell subset that are located in mucosal stratified squamous epithelium and skin epidermis. Their location is ideally suited for their function as antigen presenting cells that capture invading viruses and induce anti‐viral immunity.
Cunningham, A.L. +2 more
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Immunology & Cell Biology, 2004
Over the past 10 years a new population of cells has been the focus of much attention. The functions of these unique lymphocytes, characterized by the concomitant expression of T‐ and NK‐cell markers and thus termed NKT cells, have been implicated in many diverse aspects of immunity, including regulation of autoimmune disorders, control of tumour ...
Serani L H, Van Dommelen +1 more
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Over the past 10 years a new population of cells has been the focus of much attention. The functions of these unique lymphocytes, characterized by the concomitant expression of T‐ and NK‐cell markers and thus termed NKT cells, have been implicated in many diverse aspects of immunity, including regulation of autoimmune disorders, control of tumour ...
Serani L H, Van Dommelen +1 more
openaire +2 more sources