Results 11 to 20 of about 5,389,784 (354)
Host-directed therapies for bacterial and viral infections
Nature Reviews Drug Discovery, 2017 Despite the recent increase in the development of antivirals and antibiotics, antimicrobial resistance and the lack of broad-spectrum virus-targeting drugs are still important issues and additional alternative approaches to treat infectious diseases are ...
S. Kaufmann +3 more
semanticscholar +3 more sources
Sex Differences in Immunity to Viral Infections
Frontiers in Immunology, 2021 The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias in COVID-19 disease severity is hypothesized to be mediated by sex differential ...
H. Jacobsen, S. Klein
semanticscholar +1 more source
Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs
International Journal of Biological Macromolecules, 2021 The infectious microscopic viruses invade living cells to reproduce themselves, and causes chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to death if not treated.
D. R. Tompa +3 more
semanticscholar +1 more source
Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]
, 2018 The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan +3 more
core +5 more sources
Microbiota regulation of viral infections through interferon signaling
Trends in Microbiology, 2022 The interferon (IFN) response is the major early innate immune response against invading viral pathogens and is even capable of mediating sterilizing antiviral immunity without the support of the adaptive immune system.
Nurul I. Wirusanti +2 more
semanticscholar +1 more source
STAT1 and Its Crucial Role in the Control of Viral Infections
International Journal of Molecular Sciences, 2022 The signal transducer and activator of transcription (STAT) 1 protein plays a key role in the immune response against viruses and other pathogens by transducing, in the nucleus, the signal from type I, type II and type III IFNs.
M. Tolomeo, A. Cavalli, A. Cascio
semanticscholar +1 more source
Viruses, 2022 We aimed to review the existing literature on the different types of neutralization assays and international standards for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Kuan-Ting Liu +4 more
doaj +1 more source
Проблемы особо опасных инфекций, 2022 The aim of the study was to assess the dynamics of seroprevalence to SARS-CoV-2 in various population groups during the initial period of herd immunity formation based on multivariate analysis using logit regression models.Materials and methods.
V. A. Mishchenko +10 more
doaj +1 more source
Seasonality of Respiratory Viral Infections.
Annual Review of Virology, 2020 The seasonal cycle of respiratory viral diseases has been widely recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit the human population like clockwork in the winter season in temperate regions.
Miyu Moriyama +2 more
semanticscholar +1 more source
Viral Infections, the Microbiome, and Probiotics
Frontiers in Cellular and Infection Microbiology, 2021 Viral infections continue to cause considerable morbidity and mortality around the world. Recent rises in these infections are likely due to complex and multifactorial external drivers, including climate change, the increased mobility of people and goods
Ashton Harper +8 more
semanticscholar +1 more source