Results 31 to 40 of about 5,389,784 (354)

COVID‑19 Pandemic: Effect of Specific and Non-Specific Prevention Measures on the Risk of SARS‑CoV‑2 Infection in Employees of Healthcare Organizations

open access: yesПроблемы особо опасных инфекций, 2023
From the very onset of SARS‑CoV‑2 spreading, active involvement in the COVID‑19 epidemic process made the healthcare professionals (HCPs) a vulnerable group with higher risks of contracting the disease, severe course and fatal outcome.The aim.
I. A. Egorov   +13 more
doaj   +1 more source

A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation [PDF]

open access: yes, 2019
Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme ...
Chaminda, Gunawardene D.   +2 more
core   +1 more source

JAK-STAT Pathway: A Novel Target to Tackle Viral Infections

open access: yesViruses, 2021
Modulation of the antiviral innate immune response has been proposed as a putative cellular target for the development of novel pan-viral therapeutic strategies.
I. Ezeonwumelu   +2 more
semanticscholar   +1 more source

MITAgating Viral Infection [PDF]

open access: yesImmunity, 2008
Two recent papers, one in this issue of Immunity (Zhong et al., 2008), report the identification of a membrane protein, termed MITA or STING, that activates the transcription factor IRF3 to induce type-I interferons to mitigate viral infection.
Zeng, Wenwen, Chen, Zhijian J.
openaire   +2 more sources

Review of current issues of diagnosis and prevention of blood-borne nosocomial viral infections

open access: yesВопросы вирусологии, 2019
Provision of infection security in transplantology and transfusiology is a challenging and significant problem that depends on the quality of medical donor selection and laboratory diagnosis of the blood collected.
V. G. Akimkin   +5 more
doaj   +1 more source

To the question of the relevance of the development and prospects for the use of the bacteriophage Streptococcus pneumoniae

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2022
Introduction. The prevalence of Streptococcus pneumoniae strains causing invasive forms of pneumococcal infection and the growing rates of antibiotic resistance of individual serotypes of the pathogen pose a number of urgent and socially significant ...
Yuliya A. Zakharova   +2 more
doaj   +1 more source

Role of Mitochondria in Viral Infections

open access: yesLife, 2021
Viral diseases account for an increasing proportion of deaths worldwide. Viruses maneuver host cell machinery in an attempt to subvert the intracellular environment favorable for their replication.
Srikanth Elesela, N. Lukacs
semanticscholar   +1 more source

THE ROLE OF THE NEONATAL FC RECEPTOR IN THE UNCOATING OF ECHOVIRUSES AND COXSACKIEVIRUS A9

open access: yesВопросы вирусологии, 2019
The aim of this study was to determine the role of the human neonatal receptor for the Fc fragment of IgG (hFcRn) as a common uncoating cellular receptor for echoviruses and coxsackievirus A9 during infection of human rhabdomyosarcoma (RD) cells ...
P. S. Usoltseva   +4 more
doaj   +1 more source

Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells

open access: yesScientific Reports, 2022
Many therapeutic antibodies (Abs) and mRNA vaccines, both targeting SARS-CoV-2 spike protein (S-protein), have been developed and approved in order to combat the ongoing COVID-19 pandemic. In consideration of these developments, a common concern has been
Jun Shimizu   +11 more
doaj   +1 more source

Stability of SARS-CoV-2 Spike G614 Variant Surpasses That of the D614 Variant after Cold Storage

open access: yesmSphere, 2021
It has been observed that variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more stable and infectious after storage at −20°C than at 4°C.
Sheng-Yu Huang   +12 more
doaj   +1 more source

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