Results 131 to 140 of about 253,930 (319)

A simple relationship between viral load and survival time in HIV-1 infection [PDF]

, 1999
Ramy Arnaout, Alun L. Lloyd, Thomas R. OʼBrien, James J. Goedert, John M. Leonard, Martin A. Nowak   +5 more
openalex   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Human Immunodeficiency Virus (HIV) viral load suppression status and associated factors among pregnant women receiving Highly Active Antiretroviral Therapy (HAART) in Ethiopia

Virology Journal
Background Mothers with an undetectable viral load pose no risk of transmitting the Human Immunodeficiency Virus (HIV) to their fetuses. However, there is limited information on the HIV viral suppression status (≤ 1000 RNA copies/mL) among pregnant ...
Getnet Hailu, Abrham Keraleme, Kidist Zealiyas, Asdesach Tesema, Negash Nuramed, Feven Girmachew, Daniel Melese, Saro Abdella, Jalleta Bulti, Getachew Tollera, Mesay Hailu, Kalkidan Yibeltal   +11 more
doaj   +1 more source

HIV elimination and population viral load [PDF]

The Lancet HIV, 2016
Okano, Justin T, Gerstoft, Jan, Obel, Niels, Blower, Sally   +3 more
openaire   +5 more sources

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

Antigenic Cooperation in Viral Populations: Redistribution of Loads Among Altruistic Viruses and Maximal Load per Altruist [PDF]

arXiv
The paper continues the study of the phenomenon of local immunodeficiency (LI) in viral cross-immunoreactivity networks, with a focus on the roles and interactions between altruistic and persistent viral variants. As always, only the state of stable (i.e. observable) LI is analysed.
arxiv  

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Advanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa, Marija Dimitrievska, Cong Wang, Chenlei Gu, Ningjia Sun, Katarzyna Romańczuk, Pawel Karpinski, Łukasz Łaczmański, John A. McGrath, Joanna Jacków‐Malinowska, Ciro Chiappini   +10 more
wiley   +1 more source

Recombinant Human Gamma Interferon in Human Immunodeficiency Virus-Infected Children: Safety, CD4⁺-Lymphocyte Count, Viral Load, and Neutrophil Function (AIDS Clinical Trials Group Protocol 211) [PDF]

, 1999
William T. Shearer, Mark W. Kline, Stuart L. Abramson, Terence Fenton, Stuart E. Starr, Steven D. Douglas   +5 more
openalex   +1 more source

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

HIV Viral Loads Reach Steady State in the United States

, 1999
James B. Peter
openalex   +1 more source