Results 111 to 120 of about 466,204 (299)

HPV16/HPV58 viral load is non-linearly correlated with cervical lesions and can be used as a triage marker

open access: yesInfectious Agents and Cancer
The significance of viral load from high-risk human papillomavirus (HR-HPV) in the detection of cervical lesions is still debated. This study aims to assess the correlation between the viral load of the most common high-risk genotypes (HPV16, HPV18 ...
Jie Zhou   +5 more
doaj   +1 more source

Evaluation of quality control viral load HIV results from two laboratories in Maputo, after the 3rd Congress of Laboratory Quality Control for Portuguese-Speaking Countries, Mozambique [PDF]

open access: yes, 2019
The Project of Laboratory Quality Improvement for Portuguese Speaking Countries (ProMeQuaLab) is based on three major work tools: education, training and monitoring of quality control measures, in order to build capacity to implement and sustain good ...
Aguiar, Carmen   +8 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

ANALISIS GAMBARAN JUMLAH LEUKOSIT, VIRAL LOAD DAN KEPATUHAN MINUM OBAT ARV PADA ORANG DENGAN HIV (ODHIV)

open access: yesJurnal Ilmiah Kesehatan
Abstrak    HIV atau Human Immunodeficiency Virus yang menginfeksi sel darah putih dapat menyebabkan turunnya kekebalan tubuh manusia. Akibat menurunnya kekebalan tubuh maka orang tersebut sangat mudah terkena berbagai penyakit opurtunistik ...
Ari Setyaningsih, Yogi Khoirul Abror
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

HIV viral load algorithm

open access: yes, 2020
We have read with interest the study published by Shoufri et al. [1] and share the idea that the current application of the WHO viral load algorithm does not allow for effective management of patients with virological failure, whereas the emergence of HIV drug resistance, so-called the fourth HIV epidemic, is obvious [2].
Breton, Guillaume   +8 more
openaire   +1 more source

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